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SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8+ T cells.
Celada SI, Lim CX, Carisey AF, Ochsner SA, Arce Deza CF, Rexie P, Poli De Frias F, Cardenas-Castillo R, Polverino F, Hengstschläger M, Tsoyi K, McKenna NJ, Kheradmand F, Weichhart T, Rosas IO, Van Kaer L, Celada LJ. Celada SI, et al. Among authors: celada lj. Sci Transl Med. 2023 Sep 13;15(713):eade2581. doi: 10.1126/scitranslmed.ade2581. Epub 2023 Sep 13. Sci Transl Med. 2023. PMID: 37703351
PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.
Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS Jr, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP. Celada LJ, et al. Sci Transl Med. 2018 Sep 26;10(460):eaar8356. doi: 10.1126/scitranslmed.aar8356. Sci Transl Med. 2018. PMID: 30257954 Free PMC article.
CD148 Deficiency in Fibroblasts Promotes the Development of Pulmonary Fibrosis.
Tsoyi K, Liang X, De Rossi G, Ryter SW, Xiong K, Chu SG, Liu X, Ith B, Celada LJ, Romero F, Robertson MJ, Esposito AJ, Poli S, El-Chemaly S, Perrella MA, Shi Y, Whiteford J, Rosas IO. Tsoyi K, et al. Among authors: celada lj. Am J Respir Crit Care Med. 2021 Aug 1;204(3):312-325. doi: 10.1164/rccm.202008-3100OC. Am J Respir Crit Care Med. 2021. PMID: 33784491 Free PMC article.
Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts.
Tsoyi K, Esposito AJ, Sun B, Bowen RG, Xiong K, Poli F, Cardenas R, Chu SG, Liang X, Ryter SW, Beeton C, Doyle TJ, Robertson MJ, Celada LJ, Romero F, El-Chemaly SY, Perrella MA, Ho IC, Rosas IO. Tsoyi K, et al. Among authors: celada lj. Sci Rep. 2022 Feb 18;12(1):2847. doi: 10.1038/s41598-022-06678-7. Sci Rep. 2022. PMID: 35181688 Free PMC article.
Blockade of the programmed death-1 pathway restores sarcoidosis CD4(+) T-cell proliferative capacity.
Braun NA, Celada LJ, Herazo-Maya JD, Abraham S, Shaginurova G, Sevin CM, Grutters J, Culver DA, Dworski R, Sheller J, Massion PP, Polosukhin VV, Johnson JE, Kaminski N, Wilkes DS, Oswald-Richter KA, Drake WP. Braun NA, et al. Among authors: celada lj. Am J Respir Crit Care Med. 2014 Sep 1;190(5):560-71. doi: 10.1164/rccm.201401-0188OC. Am J Respir Crit Care Med. 2014. PMID: 25073001 Free PMC article.
13 results