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N-Acetylcysteine overcomes epalrestat-mediated increase of toxic 4-hydroxy-2-nonenal and potentiates the anti-arthritic effect of epalrestat in AIA model.
Wang L, Huang B, Zeng Y, Yang J, Li Z, Ng JPL, Xu X, Su L, Yun X, Qu L, Chen R, Luo W, Wang Y, Chen C, Yang L, Qu Y, Zhang W, Chan JTW, Wang X, Law BYK, Mok SWF, Chung SK, Wong VKW. Wang L, et al. Among authors: zhang w. Int J Biol Sci. 2023 Aug 6;19(13):4082-4102. doi: 10.7150/ijbs.85028. eCollection 2023. Int J Biol Sci. 2023. PMID: 37705749 Free PMC article.
Keratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch.
Duan Y, Sun Y, Zhang F, Zhang WK, Wang D, Wang Y, Cao X, Hu W, Xie C, Cuppoletti J, Magin TM, Wang H, Wu Z, Li N, Huang P. Duan Y, et al. Among authors: zhang wk, zhang f. J Biol Chem. 2012 Nov 23;287(48):40547-59. doi: 10.1074/jbc.M112.403584. Epub 2012 Oct 8. J Biol Chem. 2012. PMID: 23045527 Free PMC article.
Mechanosensitivity of wild-type and G551D cystic fibrosis transmembrane conductance regulator (CFTR) controls regulatory volume decrease in simple epithelia.
Xie C, Cao X, Chen X, Wang D, Zhang WK, Sun Y, Hu W, Zhou Z, Wang Y, Huang P. Xie C, et al. Among authors: zhang wk. FASEB J. 2016 Apr;30(4):1579-89. doi: 10.1096/fj.15-283002. Epub 2015 Dec 18. FASEB J. 2016. PMID: 26683699 Free PMC article.
Our findings uncover a previously unrecognized mechanism underlying CFTR involvement in epithelial RVD and suggest that the mechanosensitivity of G551D CFTR might underlie the mild phenotypes resulting from this mutation.-Xie, C., Cao, X., Chen, X, Wang, D., Zhang, W …
Our findings uncover a previously unrecognized mechanism underlying CFTR involvement in epithelial RVD and suggest that the mechanosensitivi …
CFTR is a negative regulator of γδ T cell IFN-γ production and antitumor immunity.
Duan Y, Li G, Xu M, Qi X, Deng M, Lin X, Lei Z, Hu Y, Jia Z, Yang Q, Cao G, Liu Z, Wen Q, Li Z, Tang J, Zhang WK, Huang P, Zheng L, Flavell RA, Hao J, Yin Z. Duan Y, et al. Cell Mol Immunol. 2021 Aug;18(8):1934-1944. doi: 10.1038/s41423-020-0499-3. Epub 2020 Jul 15. Cell Mol Immunol. 2021. PMID: 32669666 Free PMC article.
Cost-Effectiveness Analysis of Myopia Progression Interventions in Children.
Agyekum S, Chan PP, Adjei PE, Zhang Y, Huo Z, Yip BHK, Ip P, Wong ICK, Zhang W, Tham CC, Chen LJ, Zhang XJ, Pang CP, Yam JC. Agyekum S, et al. Among authors: zhang w, zhang xj, zhang y. JAMA Netw Open. 2023 Nov 1;6(11):e2340986. doi: 10.1001/jamanetworkopen.2023.40986. JAMA Netw Open. 2023. PMID: 37917061 Free PMC article.
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