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Characterization of SARS-CoV-2 replication in human H1299/ACE2 cells: A versatile and practical infection model for antiviral research and beyond.
Salgado-Benvindo C, Tas A, Zevenhoven-Dobbe JC, van der Meer Y, Sidorov IA, Leijs AA, Wanningen P, Gelderloos AT, van Kasteren PB, Snijder EJ, van Hemert MJ. Salgado-Benvindo C, et al. Among authors: leijs aa. Antiviral Res. 2024 May 7;227:105903. doi: 10.1016/j.antiviral.2024.105903. Online ahead of print. Antiviral Res. 2024. PMID: 38723907 Free article.
SARS-CoV-2-infected human airway epithelial cell cultures uniquely lack interferon and immediate early gene responses caused by other coronaviruses.
Wang Y, Thaler M, Salgado-Benvindo C, Ly N, Leijs AA, Ninaber DK, Hansbro PM, Boedijono F, van Hemert MJ, Hiemstra PS, van der Does AM, Faiz A. Wang Y, et al. Among authors: leijs aa. Clin Transl Immunology. 2024 Apr 15;13(4):e1503. doi: 10.1002/cti2.1503. eCollection 2024. Clin Transl Immunology. 2024. PMID: 38623540 Free PMC article.
Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo.
van Huizen M, Bloeme-Ter Horst JR, de Gruyter HLM, Geurink PP, van der Heden van Noort GJ, Knaap RCM, Nelemans T, Ogando NS, Leijs AA, Urakova N, Mark BL, Snijder EJ, Myeni SK, Kikkert M. van Huizen M, et al. Among authors: leijs aa. PLoS Pathog. 2024 Mar 25;20(3):e1012100. doi: 10.1371/journal.ppat.1012100. eCollection 2024 Mar. PLoS Pathog. 2024. PMID: 38527094 Free PMC article.
Honokiol Inhibits SARS-CoV-2 Replication in Cell Culture at a Post-Entry Step.
Salgado-Benvindo C, Leijs AA, Thaler M, Tas A, Arbiser JL, Snijder EJ, van Hemert MJ. Salgado-Benvindo C, et al. Among authors: leijs aa. Microbiol Spectr. 2023 Jun 15;11(3):e0327322. doi: 10.1128/spectrum.03273-22. Epub 2023 May 4. Microbiol Spectr. 2023. PMID: 37212560 Free PMC article.