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mTOR-dependent loss of PON1 secretion and antiphospholipid autoantibody production underlie autoimmunity-mediated cirrhosis in transaldolase deficiency.
Winans T, Oaks Z, Choudhary G, Patel A, Huang N, Faludi T, Krakko D, Nolan J, Lewis J, Blair S, Lai Z, Landas SK, Middleton F, Asara JM, Chung SK, Wyman B, Azadi P, Banki K, Perl A. Winans T, et al. Among authors: middleton f. J Autoimmun. 2023 Nov;140:103112. doi: 10.1016/j.jaut.2023.103112. Epub 2023 Sep 22. J Autoimmun. 2023. PMID: 37742509 Free PMC article.
Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis.
Oaks Z, Patel A, Huang N, Choudhary G, Winans T, Faludi T, Krakko D, Duarte M, Lewis J, Beckford M, Blair S, Kelly R, Landas SK, Middleton FA, Asara JM, Chung SK, Fernandez DR, Banki K, Perl A. Oaks Z, et al. Among authors: middleton fa. Nat Metab. 2023 Jan;5(1):41-60. doi: 10.1038/s42255-022-00711-9. Epub 2023 Jan 19. Nat Metab. 2023. PMID: 36658399 Free PMC article.
Publisher Correction: Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis.
Oaks Z, Patel A, Huang N, Choudhary G, Winans T, Faludi T, Krakko D, Duarte M, Lewis J, Beckford M, Blair S, Kelly R, Landas SK, Middleton FA, Asara JM, Chung SK, Fernandez DR, Banki K, Perl A. Oaks Z, et al. Among authors: middleton fa. Nat Metab. 2023 Feb;5(2):349. doi: 10.1038/s42255-023-00752-8. Nat Metab. 2023. PMID: 36755183 No abstract available.
Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine.
Hanczko R, Fernandez DR, Doherty E, Qian Y, Vas G, Niland B, Telarico T, Garba A, Banerjee S, Middleton FA, Barrett D, Barcza M, Banki K, Landas SK, Perl A. Hanczko R, et al. J Clin Invest. 2009 Jun;119(6):1546-57. doi: 10.1172/JCI35722. Epub 2009 May 11. J Clin Invest. 2009. PMID: 19436114 Free PMC article.
HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.
Caza TN, Fernandez DR, Talaber G, Oaks Z, Haas M, Madaio MP, Lai ZW, Miklossy G, Singh RR, Chudakov DM, Malorni W, Middleton F, Banki K, Perl A. Caza TN, et al. Among authors: middleton f. Ann Rheum Dis. 2014 Oct;73(10):1888-97. doi: 10.1136/annrheumdis-2013-203794. Epub 2013 Jul 29. Ann Rheum Dis. 2014. PMID: 23897774 Free PMC article.
223 results