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Page 1
Identification and targeting of microbial putrescine acetylation in bloodstream infections.
Mayers JR, Varon J, Zhou RR, Daniel-Ivad M, Beaulieu C, Bholse A, Glasser NR, Lichtenauer FM, Ng J, Vera MP, Huttenhower C, Perrella MA, Clish CB, Zhao SD, Baron RM, Balskus EP. Mayers JR, et al. Among authors: daniel ivad m. bioRxiv [Preprint]. 2023 Sep 21:2023.09.21.558834. doi: 10.1101/2023.09.21.558834. bioRxiv. 2023. PMID: 37790300 Free PMC article. Preprint.
A small molecule inhibitor prevents gut bacterial genotoxin production.
Volpe MR, Velilla JA, Daniel-Ivad M, Yao JJ, Stornetta A, Villalta PW, Huang HC, Bachovchin DA, Balbo S, Gaudet R, Balskus EP. Volpe MR, et al. Among authors: daniel ivad m. Nat Chem Biol. 2023 Feb;19(2):159-167. doi: 10.1038/s41589-022-01147-8. Epub 2022 Oct 17. Nat Chem Biol. 2023. PMID: 36253549 Free PMC article.
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase.
MacAlpine J, Daniel-Ivad M, Liu Z, Yano J, Revie NM, Todd RT, Stogios PJ, Sanchez H, O'Meara TR, Tompkins TA, Savchenko A, Selmecki A, Veri AO, Andes DR, Fidel PL Jr, Robbins N, Nodwell J, Whitesell L, Cowen LE. MacAlpine J, et al. Among authors: daniel ivad m. Nat Commun. 2021 Oct 22;12(1):6151. doi: 10.1038/s41467-021-26390-w. Nat Commun. 2021. PMID: 34686660 Free PMC article.
An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris.
Iyer KR, Camara K, Daniel-Ivad M, Trilles R, Pimentel-Elardo SM, Fossen JL, Marchillo K, Liu Z, Singh S, Muñoz JF, Kim SH, Porco JA Jr, Cuomo CA, Williams NS, Ibrahim AS, Edwards JE Jr, Andes DR, Nodwell JR, Brown LE, Whitesell L, Robbins N, Cowen LE. Iyer KR, et al. Among authors: daniel ivad m. Nat Commun. 2020 Dec 22;11(1):6429. doi: 10.1038/s41467-020-20183-3. Nat Commun. 2020. PMID: 33353950 Free PMC article.
Chemical entrapment and killing of insects by bacteria.
Ho LK, Daniel-Ivad M, Jeedigunta SP, Li J, Iliadi KG, Boulianne GL, Hurd TR, Smibert CA, Nodwell JR. Ho LK, et al. Among authors: daniel ivad m. Nat Commun. 2020 Sep 14;11(1):4608. doi: 10.1038/s41467-020-18462-0. Nat Commun. 2020. PMID: 32929085 Free PMC article.
A chemical defence against phage infection.
Kronheim S, Daniel-Ivad M, Duan Z, Hwang S, Wong AI, Mantel I, Nodwell JR, Maxwell KL. Kronheim S, et al. Among authors: daniel ivad m. Nature. 2018 Dec;564(7735):283-286. doi: 10.1038/s41586-018-0767-x. Epub 2018 Dec 5. Nature. 2018. PMID: 30518855
Cyclic AMP-Independent Control of Twitching Motility in Pseudomonas aeruginosa.
Buensuceso RNC, Daniel-Ivad M, Kilmury SLN, Leighton TL, Harvey H, Howell PL, Burrows LL. Buensuceso RNC, et al. Among authors: daniel ivad m. J Bacteriol. 2017 Jul 25;199(16):e00188-17. doi: 10.1128/JB.00188-17. Print 2017 Aug 15. J Bacteriol. 2017. PMID: 28583947 Free PMC article.
The Conserved Tetratricopeptide Repeat-Containing C-Terminal Domain of Pseudomonas aeruginosa FimV Is Required for Its Cyclic AMP-Dependent and -Independent Functions.
Buensuceso RN, Nguyen Y, Zhang K, Daniel-Ivad M, Sugiman-Marangos SN, Fleetwood AD, Zhulin IB, Junop MS, Howell PL, Burrows LL. Buensuceso RN, et al. Among authors: daniel ivad m. J Bacteriol. 2016 Jul 28;198(16):2263-74. doi: 10.1128/JB.00322-16. Print 2016 Aug 15. J Bacteriol. 2016. PMID: 27297880 Free PMC article.