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biomArker-guided Duration of Antibiotic treatment in hospitalised Patients with suspecTed Sepsis (ADAPT-Sepsis): A protocol for a multicentre randomised controlled trial.
Dark P, Perkins GD, McMullan R, McAuley D, Gordon AC, Clayton J, Mistry D, Young K, Regan S, McGowan N, Stevenson M, Gates S, Carlson GL, Walsh T, Lone NI, Mouncey PR, Singer M, Wilson P, Felton T, Marshall K, Hossain AM, Lall R. Dark P, et al. Among authors: singer m. J Intensive Care Soc. 2023 Nov;24(4):427-434. doi: 10.1177/17511437231169193. Epub 2023 Apr 25. J Intensive Care Soc. 2023. PMID: 37841304 Free PMC article.
Trial of early, goal-directed resuscitation for septic shock.
Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM; ProMISe Trial Investigators. Mouncey PR, et al. Among authors: singer m. N Engl J Med. 2015 Apr 2;372(14):1301-11. doi: 10.1056/NEJMoa1500896. Epub 2015 Mar 17. N Engl J Med. 2015. PMID: 25776532 Free article. Clinical Trial.
Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, protocolised resuscitation for emerging septic shock.
Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Tan JC, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM. Mouncey PR, et al. Among authors: singer m. Health Technol Assess. 2015 Nov;19(97):i-xxv, 1-150. doi: 10.3310/hta19970. Health Technol Assess. 2015. PMID: 26597979 Free PMC article. Clinical Trial.
Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy.
Perner A, Gordon AC, De Backer D, Dimopoulos G, Russell JA, Lipman J, Jensen JU, Myburgh J, Singer M, Bellomo R, Walsh T. Perner A, et al. Among authors: singer m. Intensive Care Med. 2016 Dec;42(12):1958-1969. doi: 10.1007/s00134-016-4577-z. Epub 2016 Oct 1. Intensive Care Med. 2016. PMID: 27695884 Free article. Review.
Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis.
Gordon AC, Perkins GD, Singer M, McAuley DF, Orme RM, Santhakumaran S, Mason AJ, Cross M, Al-Beidh F, Best-Lane J, Brealey D, Nutt CL, McNamee JJ, Reschreiter H, Breen A, Liu KD, Ashby D. Gordon AC, et al. Among authors: singer m. N Engl J Med. 2016 Oct 27;375(17):1638-1648. doi: 10.1056/NEJMoa1609409. Epub 2016 Oct 5. N Engl J Med. 2016. PMID: 27705084 Free article.
Levosimendan in Sepsis.
Gordon AC, Orme RML, Singer M. Gordon AC, et al. Among authors: singer m. N Engl J Med. 2017 Feb 23;376(8):800. doi: 10.1056/NEJMc1616632. N Engl J Med. 2017. PMID: 28225677 Free article. No abstract available.
Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.
PRISM Investigators; Rowan KM, Angus DC, Bailey M, Barnato AE, Bellomo R, Canter RR, Coats TJ, Delaney A, Gimbel E, Grieve RD, Harrison DA, Higgins AM, Howe B, Huang DT, Kellum JA, Mouncey PR, Music E, Peake SL, Pike F, Reade MC, Sadique MZ, Singer M, Yealy DM. PRISM Investigators, et al. Among authors: singer m. N Engl J Med. 2017 Jun 8;376(23):2223-2234. doi: 10.1056/NEJMoa1701380. Epub 2017 Mar 21. N Engl J Med. 2017. PMID: 28320242 Free article.
The intensive care medicine research agenda on septic shock.
Perner A, Gordon AC, Angus DC, Lamontagne F, Machado F, Russell JA, Timsit JF, Marshall JC, Myburgh J, Shankar-Hari M, Singer M. Perner A, et al. Among authors: singer m. Intensive Care Med. 2017 Sep;43(9):1294-1305. doi: 10.1007/s00134-017-4821-1. Epub 2017 May 12. Intensive Care Med. 2017. PMID: 28500455 Free article. Review.
2,632 results