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The molecular basis of drug selectivity for α5 subunit-containing GABAA receptors.
Kasaragod VB, Malinauskas T, Wahid AA, Lengyel J, Knoflach F, Hardwick SW, Jones CF, Chen WN, Lucas X, El Omari K, Chirgadze DY, Aricescu AR, Cecere G, Hernandez MC, Miller PS. Kasaragod VB, et al. Among authors: el omari k. Nat Struct Mol Biol. 2023 Dec;30(12):1936-1946. doi: 10.1038/s41594-023-01133-1. Epub 2023 Oct 30. Nat Struct Mol Biol. 2023. PMID: 37903907 Free PMC article.
Production and crystallization of the C-propeptide trimer from human procollagen III.
Bourhis JM, Mariano N, Zhao Y, Walter TS, El Omari K, Delolme F, Moali C, Hulmes DJ, Aghajari N. Bourhis JM, et al. Among authors: el omari k. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1209-13. doi: 10.1107/S1744309112035294. Epub 2012 Sep 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 23027749 Free PMC article.
The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism.
Rudolf AF, Kinnebrew M, Kowatsch C, Ansell TB, El Omari K, Bishop B, Pardon E, Schwab RA, Malinauskas T, Qian M, Duman R, Covey DF, Steyaert J, Wagner A, Sansom MSP, Rohatgi R, Siebold C. Rudolf AF, et al. Among authors: el omari k. Nat Chem Biol. 2019 Oct;15(10):975-982. doi: 10.1038/s41589-019-0370-y. Epub 2019 Sep 23. Nat Chem Biol. 2019. PMID: 31548691 Free PMC article.
Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling.
Griffiths SC, Schwab RA, El Omari K, Bishop B, Iverson EJ, Malinauskas T, Dubey R, Qian M, Covey DF, Gilbert RJC, Rohatgi R, Siebold C. Griffiths SC, et al. Among authors: el omari k. Nat Commun. 2021 Dec 9;12(1):7171. doi: 10.1038/s41467-021-27475-2. Nat Commun. 2021. PMID: 34887403 Free PMC article.
Structural basis for proton coupled cystine transport by cystinosin.
Löbel M, Salphati SP, El Omari K, Wagner A, Tucker SJ, Parker JL, Newstead S. Löbel M, et al. Among authors: el omari k. Nat Commun. 2022 Aug 17;13(1):4845. doi: 10.1038/s41467-022-32589-2. Nat Commun. 2022. PMID: 35977944 Free PMC article.
Structure and function of Semaphorin-5A glycosaminoglycan interactions.
Nagy GN, Zhao XF, Karlsson R, Wang K, Duman R, Harlos K, El Omari K, Wagner A, Clausen H, Miller RL, Giger RJ, Jones EY. Nagy GN, et al. Among authors: el omari k. Nat Commun. 2024 Mar 28;15(1):2723. doi: 10.1038/s41467-024-46725-7. Nat Commun. 2024. PMID: 38548715 Free PMC article.
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Hengrung N, El Omari K, Serna Martin I, Vreede FT, Cusack S, Rambo RP, Vonrhein C, Bricogne G, Stuart DI, Grimes JM, Fodor E. Hengrung N, et al. Among authors: el omari k. Nature. 2015 Nov 5;527(7576):114-7. doi: 10.1038/nature15525. Epub 2015 Oct 26. Nature. 2015. PMID: 26503046 Free PMC article.
86 results