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Antibody-Proteolysis Targeting Chimera Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 in HER2+ Cell Lines.
Bioconjug Chem. 2023 Nov 15;34(11):2049-2054. doi: 10.1021/acs.bioconjchem.3c00366. Epub 2023 Nov 2.
Bioconjug Chem. 2023.
PMID: 37917829
Free PMC article.
An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing Kinase.
Al-Khawaldeh I, Al Yasiri MJ, Aldred GG, Basmadjian C, Bordoni C, Harnor SJ, Heptinstall AB, Hobson SJ, Jennings CE, Khalifa S, Lebraud H, Martin MP, Miller DC, Shrives HJ, de Souza JV, Stewart HL, Temple M, Thomas HD, Totobenazara J, Tucker JA, Tudhope SJ, Wang LZ, Bronowska AK, Cano C, Endicott JA, Golding BT, Hardcastle IR, Hickson I, Wedge SR, Willmore E, Noble MEM, Waring MJ.
Al-Khawaldeh I, et al. Among authors: shrives hj.
J Med Chem. 2021 Jul 22;64(14):10001-10018. doi: 10.1021/acs.jmedchem.0c01249. Epub 2021 Jul 2.
J Med Chem. 2021.
PMID: 34212719
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A Concise Enantioselective Synthesis of Fluorinated Pyrazolo-Piperidine GSK3901383A Enabled by an Organocatalytic Aza-Michael Addition.
Barron B, Edge C, Fenner S, Shrives H, Sollis S, Whiting M, Valette D.
Barron B, et al. Among authors: shrives h.
Org Lett. 2024 Mar 1;26(8):1533-1538. doi: 10.1021/acs.orglett.3c03694. Epub 2024 Feb 16.
Org Lett. 2024.
PMID: 38363757
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Synthesis of C2 Substituted Benzothiophenes via an Interrupted Pummerer/[3,3]-Sigmatropic/1,2-Migration Cascade of Benzothiophene S-Oxides.
He Z, Shrives HJ, Fernández-Salas JA, Abengózar A, Neufeld J, Yang K, Pulis AP, Procter DJ.
He Z, et al. Among authors: shrives hj.
Angew Chem Int Ed Engl. 2018 May 14;57(20):5759-5764. doi: 10.1002/anie.201801982. Epub 2018 Apr 10.
Angew Chem Int Ed Engl. 2018.
PMID: 29528177
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Regioselective synthesis of C3 alkylated and arylated benzothiophenes.
Shrives HJ, Fernández-Salas JA, Hedtke C, Pulis AP, Procter DJ.
Shrives HJ, et al.
Nat Commun. 2017 Mar 20;8:14801. doi: 10.1038/ncomms14801.
Nat Commun. 2017.
PMID: 28317882
Free PMC article.
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Sulfoxide-directed metal-free cross-couplings in the expedient synthesis of benzothiophene-based components of materials.
Eberhart AJ, Shrives H, Zhang Y, Carrër A, Parry AVS, Tate DJ, Turner ML, Procter DJ.
Eberhart AJ, et al. Among authors: shrives h.
Chem Sci. 2016 Feb 1;7(2):1281-1285. doi: 10.1039/c5sc03823e. Epub 2015 Nov 9.
Chem Sci. 2016.
PMID: 29910885
Free PMC article.
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Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics.
Eberhart AJ, Shrives HJ, Álvarez E, Carrër A, Zhang Y, Procter DJ.
Eberhart AJ, et al. Among authors: shrives hj.
Chemistry. 2015 May 11;21(20):7313. doi: 10.1002/chem.201501070. Epub 2015 Apr 1.
Chemistry. 2015.
PMID: 25832900
No abstract available.
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Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics.
Eberhart AJ, Shrives HJ, Álvarez E, Carrër A, Zhang Y, Procter DJ.
Eberhart AJ, et al. Among authors: shrives hj.
Chemistry. 2015 May 11;21(20):7428-34. doi: 10.1002/chem.201406424. Epub 2015 Mar 6.
Chemistry. 2015.
PMID: 25752800
Free PMC article.
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