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Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Maji A, Soutar CP, Zhang J, Lewandowska A, Uno BE, Yan S, Shelke Y, Murhade G, Nimerovsky E, Borcik CG, Arango AS, Lange JD, Marin-Toledo JP, Lyu Y, Bailey KL, Roady PJ, Holler JT, Khandelwal A, SantaMaria AM, Sanchez H, Juvvadi PR, Johns G, Hageman MJ, Krise J, Gebremariam T, Youssef EG, Bartizal K, Marr KA, Steinbach WJ, Ibrahim AS, Patterson TF, Wiederhold NP, Andes DR, Pogorelov TV, Schwieters CD, Fan TM, Rienstra CM, Burke MD. Maji A, et al. Among authors: pogorelov tv. Nature. 2023 Nov;623(7989):1079-1085. doi: 10.1038/s41586-023-06710-4. Epub 2023 Nov 8. Nature. 2023. PMID: 37938782 Free PMC article.
Protein-phospholipid interactions in blood clotting.
Morrissey JH, Davis-Harrison RL, Tavoosi N, Ke K, Pureza V, Boettcher JM, Clay MC, Rienstra CM, Ohkubo YZ, Pogorelov TV, Tajkhorshid E. Morrissey JH, et al. Among authors: pogorelov tv. Thromb Res. 2010 Apr;125 Suppl 1:S23-5. doi: 10.1016/j.thromres.2010.01.027. Epub 2010 Feb 4. Thromb Res. 2010. PMID: 20129649 Free PMC article. Review.
Molecular determinants of phospholipid synergy in blood clotting.
Tavoosi N, Davis-Harrison RL, Pogorelov TV, Ohkubo YZ, Arcario MJ, Clay MC, Rienstra CM, Tajkhorshid E, Morrissey JH. Tavoosi N, et al. Among authors: pogorelov tv. J Biol Chem. 2011 Jul 1;286(26):23247-53. doi: 10.1074/jbc.M111.251769. Epub 2011 May 11. J Biol Chem. 2011. PMID: 21561861 Free PMC article.
C3-OH of Amphotericin B Plays an Important Role in Ion Conductance.
Davis SA, Della Ripa LA, Hu L, Cioffi AG, Pogorelov TV, Rienstra CM, Burke MD. Davis SA, et al. Among authors: pogorelov tv. J Am Chem Soc. 2015 Dec 9;137(48):15102-4. doi: 10.1021/jacs.5b05766. Epub 2015 Nov 30. J Am Chem Soc. 2015. PMID: 26580003 Free PMC article.
Fungicidal amphotericin B sponges are assemblies of staggered asymmetric homodimers encasing large void volumes.
Lewandowska A, Soutar CP, Greenwood AI, Nimerovsky E, De Lio AM, Holler JT, Hisao GS, Khandelwal A, Zhang J, SantaMaria AM, Schwieters CD, Pogorelov TV, Burke MD, Rienstra CM. Lewandowska A, et al. Among authors: pogorelov tv. Nat Struct Mol Biol. 2021 Dec;28(12):972-981. doi: 10.1038/s41594-021-00685-4. Epub 2021 Dec 9. Nat Struct Mol Biol. 2021. PMID: 34887566 Free PMC article.
Segmental Dynamics of Membranous Cholesterol are Coupled.
Della Ripa LA, Courtney JM, Phinney SM, Borcik CG, Burke MD, Rienstra CM, Pogorelov TV. Della Ripa LA, et al. Among authors: pogorelov tv. J Am Chem Soc. 2023 Jul 19;145(28):15043-15048. doi: 10.1021/jacs.3c01775. Epub 2023 Jul 6. J Am Chem Soc. 2023. PMID: 37410392
41 results