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Identification and targeting of treatment resistant progenitor populations in T-cell Acute Lymphoblastic Leukemia.
Tan K, Xu J, Chen C, Vincent T, Pölönen P, Hu J, Yoshimura S, Yu W, Sussman J, Chen CH, Li E, Diorio C, Shraim R, Newman H, Uppuluri L, Li A, Chen G, Bandyopadhyay S, Wu D, Ding YY, Xu J, Lim T, Hsu M, Thadi A, Ahn KJ, Wu CY, Peng J, Sun Y, Wang A, Mehta R, Frank D, Meyer L, Loh M, Raetz E, Chen Z, Wood B, Devidas M, Dunsmore K, Winter S, Chang TC, Wu G, Pounds S, Zhang N, Carroll W, Hunger S, Bernt K, Yang J, Mullighan C, Teachey D. Tan K, et al. Among authors: chen z, chen ch, chen c, chen g. Res Sq [Preprint]. 2023 Oct 30:rs.3.rs-3487715. doi: 10.21203/rs.3.rs-3487715/v1. Res Sq. 2023. PMID: 37961674 Free PMC article. Preprint.
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution.
Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, Gray JW, Guinney J, Hanlon SE, Hughes SK, Hwang ES, Iacobuzio-Donahue CA, Jané-Valbuena J, Johnson BE, Lau KS, Lively T, Mazzilli SA, Pe'er D, Santagata S, Shalek AK, Schapiro D, Snyder MP, Sorger PK, Spira AE, Srivastava S, Tan K, West RB, Williams EH; Human Tumor Atlas Network. Rozenblatt-Rosen O, et al. Cell. 2020 Apr 16;181(2):236-249. doi: 10.1016/j.cell.2020.03.053. Cell. 2020. PMID: 32302568 Free PMC article. Review.
Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy.
Chen GM, Chen C, Das RK, Gao P, Chen CH, Bandyopadhyay S, Ding YY, Uzun Y, Yu W, Zhu Q, Myers RM, Grupp SA, Barrett DM, Tan K. Chen GM, et al. Among authors: chen ch, chen c. Cancer Discov. 2021 Sep;11(9):2186-2199. doi: 10.1158/2159-8290.CD-20-1677. Epub 2021 Apr 5. Cancer Discov. 2021. PMID: 33820778 Free PMC article. Clinical Trial.
Network Analysis Reveals Synergistic Genetic Dependencies for Rational Combination Therapy in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia.
Ding YY, Kim H, Madden K, Loftus JP, Chen GM, Allen DH, Zhang R, Xu J, Chen CH, Hu Y, Tasian SK, Tan K. Ding YY, et al. Among authors: chen ch, chen gm. Clin Cancer Res. 2021 Sep 15;27(18):5109-5122. doi: 10.1158/1078-0432.CCR-21-0553. Epub 2021 Jul 1. Clin Cancer Res. 2021. PMID: 34210682 Free PMC article.
Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia.
Chen C, Yu W, Alikarami F, Qiu Q, Chen CH, Flournoy J, Gao P, Uzun Y, Fang L, Davenport JW, Hu Y, Zhu Q, Wang K, Libbrecht C, Felmeister A, Rozich I, Ding YY, Hunger SP, Felix CA, Wu H, Brown PA, Guest EM, Barrett DM, Bernt KM, Tan K. Chen C, et al. Among authors: chen ch. Blood. 2022 Apr 7;139(14):2198-2211. doi: 10.1182/blood.2021013442. Blood. 2022. PMID: 34864916 Free PMC article.
Isolation of Epithelial and Stromal Cells from Colon Tissues in Homeostasis and Under Inflammatory Conditions.
Morral C, Ghinnagow R, Karakasheva T, Zhou Y, Thadi A, Li N, Yoshor B, Soto GE, Chen CH, Aleynick D, Weinbrom S, Fulton M, Uzun Y, Bewtra M, Kelsen JR, Lengner CJ, Tan K, Minn AJ, Hamilton KE. Morral C, et al. Among authors: chen ch. Bio Protoc. 2023 Sep 20;13(18):e4825. doi: 10.21769/BioProtoc.4825. eCollection 2023 Sep 20. Bio Protoc. 2023. PMID: 37753470 Free PMC article.
8,818 results