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Sex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in females.
Wang YT, Therriault J, Servaes S, Tissot C, Rahmouni N, Macedo AC, Fernandez-Arias J, Mathotaarachchi SS, Benedet AL, Stevenson J, Ashton NJ, Lussier FZ, Pascoal TA, Zetterberg H, Rajah MN, Blennow K, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Wang YT, et al. Among authors: mathotaarachchi ss. Brain. 2024 Apr 4;147(4):1497-1510. doi: 10.1093/brain/awad397. Brain. 2024. PMID: 37988283 Free PMC article.
Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β.
Therriault J, Benedet AL, Pascoal TA, Mathotaarachchi S, Chamoun M, Savard M, Thomas E, Kang MS, Lussier F, Tissot C, Parsons M, Qureshi MNI, Vitali P, Massarweh G, Soucy JP, Rej S, Saha-Chaudhuri P, Gauthier S, Rosa-Neto P. Therriault J, et al. JAMA Neurol. 2020 Apr 1;77(4):470-479. doi: 10.1001/jamaneurol.2019.4421. JAMA Neurol. 2020. PMID: 31860000 Free PMC article.
18F-MK-6240 PET for early and late detection of neurofibrillary tangles.
Pascoal TA, Therriault J, Benedet AL, Savard M, Lussier FZ, Chamoun M, Tissot C, Qureshi MNI, Kang MS, Mathotaarachchi S, Stevenson J, Hopewell R, Massarweh G, Soucy JP, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Brain. 2020 Sep 1;143(9):2818-2830. doi: 10.1093/brain/awaa180. Brain. 2020. PMID: 32671408
Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer's disease.
Benedet AL, Leuzy A, Pascoal TA, Ashton NJ, Mathotaarachchi S, Savard M, Therriault J, Kang MS, Chamoun M, Schöll M, Zimmer ER, Gauthier S, Labbe A, Zetterberg H, Rosa-Neto P, Blennow K; Alzheimer’s Disease Neuroimaging Initiative. Benedet AL, et al. Brain. 2020 Dec 1;143(12):3793-3804. doi: 10.1093/brain/awaa342. Brain. 2020. PMID: 33210117 Free PMC article.
Plasma levels of phosphorylated tau 181 are associated with cerebral metabolic dysfunction in cognitively impaired and amyloid-positive individuals.
Lussier FZ, Benedet AL, Therriault J, Pascoal TA, Tissot C, Chamoun M, Mathotaarachchi S, Savard M, Ashton NJ, Karikari TK, Rodriguez JL, Snellman A, Bezgin G, Kang MS, Fernandez Arias J, Wang YT, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Lussier FZ, et al. Brain Commun. 2021 Apr 15;3(2):fcab073. doi: 10.1093/braincomms/fcab073. eCollection 2021. Brain Commun. 2021. PMID: 33959711 Free PMC article.
Interactive rather than independent effect of APOE and sex potentiates tau deposition in women.
Wang YT, Pascoal TA, Therriault J, Kang MS, Benedet AL, Savard M, Tissot C, Lussier FZ, Arias JF, Mathotaarachchi S, Rajah MN, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Wang YT, et al. Brain Commun. 2021 Jun 7;3(2):fcab126. doi: 10.1093/braincomms/fcab126. eCollection 2021. Brain Commun. 2021. PMID: 34189460 Free PMC article.
Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages.
Pascoal TA, Benedet AL, Tudorascu DL, Therriault J, Mathotaarachchi S, Savard M, Lussier FZ, Tissot C, Chamoun M, Kang MS, Stevenson J, Massarweh G, Guiot MC, Soucy JP, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Brain. 2021 Dec 16;144(11):3517-3528. doi: 10.1093/brain/awab248. Brain. 2021. PMID: 34515754 Free PMC article.
Amyloid-dependent and amyloid-independent effects of Tau in individuals without dementia.
Therriault J, Pascoal TA, Sefranek M, Mathotaarachchi S, Benedet AL, Chamoun M, Lussier FZ, Tissot C, Bellaver B, Lukasewicz PS, Zimmer ER, Saha-Chaudhuri P, Gauthier S, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Therriault J, et al. Ann Clin Transl Neurol. 2021 Oct;8(10):2083-2092. doi: 10.1002/acn3.51457. Epub 2021 Oct 7. Ann Clin Transl Neurol. 2021. PMID: 34617688 Free PMC article.
Verbal memory formation across PET-based Braak stages of tau accumulation in Alzheimer's disease.
Fernández Arias J, Therriault J, Thomas E, Lussier FZ, Bezgin G, Tissot C, Servaes S, Mathotaarachchi SS, Schoemaker D, Stevenson J, Rahmouni N, Kang MS, Pallen V, Poltronetti NM, Wang YT, Kunach P, Chamoun M, Quispialaya S KM, Vitali P, Massarweh G, Gauthier S, Rajah MN, Pascoal T, Rosa-Neto P. Fernández Arias J, et al. Among authors: mathotaarachchi ss. Brain Commun. 2023 May 18;5(3):fcad146. doi: 10.1093/braincomms/fcad146. eCollection 2023. Brain Commun. 2023. PMID: 37252014 Free PMC article.
61 results