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PTEN deficiency promotes pathological vascular remodeling of human coronary arteries.
Moulton KS, Li M, Strand K, Burgett S, McClatchey P, Tucker R, Furgeson SB, Lu S, Kirkpatrick B, Cleveland JC, Nemenoff RA, Ambardekar AV, Weiser-Evans MC. Moulton KS, et al. JCI Insight. 2018 Feb 22;3(4):e97228. doi: 10.1172/jci.insight.97228. eCollection 2018 Feb 22. JCI Insight. 2018. PMID: 29467331 Free PMC article.
Redistribution of the chromatin remodeler Brg1 directs smooth muscle-derived adventitial progenitor-to-myofibroblast differentiation and vascular fibrosis.
Jolly AJ, Lu S, Dubner AM, Strand KA, Mutryn MF, Pilotti-Riley A, Danis EP, Nemenoff RA, Moulton KS, Majesky MW, Weiser-Evans MC. Jolly AJ, et al. Among authors: weiser evans mc. JCI Insight. 2023 May 8;8(9):e164862. doi: 10.1172/jci.insight.164862. JCI Insight. 2023. PMID: 36976650 Free PMC article.
High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling.
Strand KA, Lu S, Mutryn MF, Li L, Zhou Q, Enyart BT, Jolly AJ, Dubner AM, Moulton KS, Nemenoff RA, Koch KA, LaBarbera DV, Weiser-Evans MCM. Strand KA, et al. Arterioscler Thromb Vasc Biol. 2020 Aug;40(8):1854-1869. doi: 10.1161/ATVBAHA.120.314458. Epub 2020 Jun 25. Arterioscler Thromb Vasc Biol. 2020. PMID: 32580634 Free PMC article.
84 results