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Sustained Vision Recovery by OSK Gene Therapy in a Mouse Model of Glaucoma.
Karg MM, Lu YR, Refaian N, Cameron J, Hoffmann E, Hoppe C, Shirahama S, Shah M, Krasniqi D, Krishnan A, Shrestha M, Guo Y, Cermak JM, Walthier M, Broniowska K, Rosenzweig-Lipson S, Gregory-Ksander M, Sinclair DA, Ksander BR. Karg MM, et al. Among authors: sinclair da. Cell Reprogram. 2023 Dec;25(6):288-299. doi: 10.1089/cell.2023.0074. Epub 2023 Dec 7. Cell Reprogram. 2023. PMID: 38060815
Chemically induced reprogramming to reverse cellular aging.
Yang JH, Petty CA, Dixon-McDougall T, Lopez MV, Tyshkovskiy A, Maybury-Lewis S, Tian X, Ibrahim N, Chen Z, Griffin PT, Arnold M, Li J, Martinez OA, Behn A, Rogers-Hammond R, Angeli S, Gladyshev VN, Sinclair DA. Yang JH, et al. Among authors: sinclair da. Aging (Albany NY). 2023 Jul 12;15(13):5966-5989. doi: 10.18632/aging.204896. Epub 2023 Jul 12. Aging (Albany NY). 2023. PMID: 37437248 Free PMC article.
Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study.
Pencina KM, Valderrabano R, Wipper B, Orkaby AR, Reid KF, Storer T, Lin AP, Merugumala S, Wilson L, Latham N, Ghattas-Puylara C, Ozimek NE, Cheng M, Bhargava A, Memish-Beleva Y, Lawney B, Lavu S, Swain PM, Apte RS, Sinclair DA, Livingston D, Bhasin S. Pencina KM, et al. Among authors: sinclair da. J Clin Endocrinol Metab. 2023 Jul 14;108(8):1968-1980. doi: 10.1210/clinem/dgad027. J Clin Endocrinol Metab. 2023. PMID: 36740954 Clinical Trial.
Restricting mealtime ameliorates neurodegeneration.
Tian X, Sinclair DA. Tian X, et al. Among authors: sinclair da. Cell Metab. 2023 Oct 3;35(10):1673-1674. doi: 10.1016/j.cmet.2023.09.006. Cell Metab. 2023. PMID: 37793341
Human trials exploring anti-aging medicines.
Guarente L, Sinclair DA, Kroemer G. Guarente L, et al. Among authors: sinclair da. Cell Metab. 2024 Feb 6;36(2):354-376. doi: 10.1016/j.cmet.2023.12.007. Epub 2024 Jan 4. Cell Metab. 2024. PMID: 38181790 Review.
Correction: The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth.
Firestein R, Blander G, Michan S, Oberdoerffer P, Ogino S, Campbell J, Bhimavarapu A, Luikenhuis S, de Cabo R, Fuchs C, Hahn WC, Guarente LP, Sinclair DA. Firestein R, et al. Among authors: sinclair da. PLoS One. 2024 Jun 6;19(6):e0305277. doi: 10.1371/journal.pone.0305277. eCollection 2024. PLoS One. 2024. PMID: 38843127 Free PMC article.
278 results