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Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Hellman LM, Foley KC, Singh NK, Alonso JA, Riley TP, Devlin JR, Ayres CM, Keller GLJ, Zhang Y, Vander Kooi CW, Nishimura MI, Baker BM. Hellman LM, et al. Among authors: keller glj. Mol Ther. 2019 Feb 6;27(2):300-313. doi: 10.1016/j.ymthe.2018.12.010. Epub 2018 Dec 14. Mol Ther. 2019. PMID: 30617019 Free PMC article.
Structure Based Prediction of Neoantigen Immunogenicity.
Riley TP, Keller GLJ, Smith AR, Davancaze LM, Arbuiso AG, Devlin JR, Baker BM. Riley TP, et al. Among authors: keller glj. Front Immunol. 2019 Aug 28;10:2047. doi: 10.3389/fimmu.2019.02047. eCollection 2019. Front Immunol. 2019. PMID: 31555277 Free PMC article.
Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Devlin JR, Alonso JA, Ayres CM, Keller GLJ, Bobisse S, Vander Kooi CW, Coukos G, Gfeller D, Harari A, Baker BM. Devlin JR, et al. Among authors: keller glj. Nat Chem Biol. 2020 Nov;16(11):1269-1276. doi: 10.1038/s41589-020-0610-1. Epub 2020 Aug 17. Nat Chem Biol. 2020. PMID: 32807968 Free PMC article.
Reversion analysis reveals the in vivo immunogenicity of a poorly MHC I-binding cancer neoepitope.
Ebrahimi-Nik H, Moussa M, Englander RP, Singhaviranon S, Michaux J, Pak H, Miyadera H, Corwin WL, Keller GLJ, Hagymasi AT, Shcheglova TV, Coukos G, Baker BM, Mandoiu II, Bassani-Sternberg M, Srivastava PK. Ebrahimi-Nik H, et al. Among authors: keller glj. Nat Commun. 2021 Nov 5;12(1):6423. doi: 10.1038/s41467-021-26646-5. Nat Commun. 2021. PMID: 34741035 Free PMC article.
11 results