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Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury.
Wen Y, Su E, Xu L, Menez S, Moledina DG, Obeid W, Palevsky PM, Mansour SG, Devarajan P, Cantley LG, Cahan P, Parikh CR; Kidney Precision Medicine Project; Translational Investigation of Biomarker Endpoint of Acute Kidney Injury. Wen Y, et al. Among authors: xu l. Sci Transl Med. 2023 Dec 13;15(726):eade7287. doi: 10.1126/scitranslmed.ade7287. Epub 2023 Dec 13. Sci Transl Med. 2023. PMID: 38091407
Longitudinal biomarkers and kidney disease progression after acute kidney injury.
Wen Y, Xu L, Melchinger I, Thiessen-Philbrook H, Moledina DG, Coca SG, Hsu CY, Go AS, Liu KD, Siew ED, Ikizler TA, Chinchilli VM, Kaufman JS, Kimmel PL, Himmelfarb J, Cantley LG, Parikh CR; ASSESS-AKI Consortium. Wen Y, et al. Among authors: xu l. JCI Insight. 2023 May 8;8(9):e167731. doi: 10.1172/jci.insight.167731. JCI Insight. 2023. PMID: 36951957 Free PMC article.
The ASSESS-AKI Study found urinary epidermal growth factor is associated with reduced risk of major adverse kidney events.
Menez S, Wen Y, Xu L, Moledina DG, Thiessen-Philbrook H, Hu D, Obeid W, Bhatraju PK, Ikizler TA, Siew ED, Chinchilli VM, Garg AX, Go AS, Liu KD, Kaufman JS, Kimmel PL, Himmelfarb J, Coca SG, Cantley LG, Parikh CR. Menez S, et al. Among authors: xu l. Kidney Int. 2023 Dec;104(6):1194-1205. doi: 10.1016/j.kint.2023.08.007. Epub 2023 Aug 29. Kidney Int. 2023. PMID: 37652206 Free article.
Urine Uromodulin as a Biomarker of Kidney Tubulointerstitial Fibrosis.
Melchinger H, Calderon-Gutierrez F, Obeid W, Xu L, Shaw MM, Luciano RL, Kuperman M, Moeckel GW, Kashgarian M, Wilson FP, Parikh CR, Moledina DG. Melchinger H, et al. Among authors: xu l. Clin J Am Soc Nephrol. 2022 Sep;17(9):1284-1292. doi: 10.2215/CJN.04360422. Epub 2022 Aug 10. Clin J Am Soc Nephrol. 2022. PMID: 35948365 Free PMC article.
Biomarkers of inflammation and repair in kidney disease progression.
Puthumana J, Thiessen-Philbrook H, Xu L, Coca SG, Garg AX, Himmelfarb J, Bhatraju PK, Ikizler TA, Siew ED, Ware LB, Liu KD, Go AS, Kaufman JS, Kimmel PL, Chinchilli VM, Cantley LG, Parikh CR. Puthumana J, et al. Among authors: xu l. J Clin Invest. 2021 Feb 1;131(3):e139927. doi: 10.1172/JCI139927. J Clin Invest. 2021. PMID: 33290282 Free PMC article.
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