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HIV vaccines induce CD8+ T cells with low antigen receptor sensitivity.
Migueles SA, Nettere DM, Gavil NV, Wang LT, Toulmin SA, Kelly EP, Ward AJ, Lin S, Thompson SA, Peterson BA, Abdeen CS, Sclafani CR, Pryal PF, Leach BG, Ludwig AK, Rogan DC, Przygonska PA, Cattani A, Imamichi H, Sachs A, Cafri G, Huang NN, Patamawenu A, Liang CJ, Hallahan CW, Kambach DM, Han EX, Coupet T, Chen J, Moir SL, Chun TW, Coates EE, Ledgerwood J, Schmidt J, Taillandier-Coindard M, Michaux J, Pak H, Bassani-Sternberg M, Frahm N, McElrath MJ, Connors M. Migueles SA, et al. Among authors: nettere dm. Science. 2023 Dec 15;382(6676):1270-1276. doi: 10.1126/science.adg0514. Epub 2023 Dec 14. Science. 2023. PMID: 38096385
Conjugation of HIV-1 envelope to hepatitis B surface antigen alters vaccine responses in rhesus macaques.
Nettere D, Unnithan S, Rodgers N, Nohara J, Cray P, Berry M, Jones C, Armand L, Li SH, Berendam SJ, Fouda GG, Cain DW, Spence TN, Granek JA, Davenport CA, Edwards RJ, Wiehe K, Van Rompay KKA, Moody MA, Permar SR, Pollara J. Nettere D, et al. NPJ Vaccines. 2023 Nov 24;8(1):183. doi: 10.1038/s41541-023-00775-y. NPJ Vaccines. 2023. PMID: 38001122 Free PMC article.