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Lipid Tales: Optimizing Arylomycin Membrane Anchors.
Koehler MFT, Chen YC, Chen Y, Chen Y, Crawford JJ, Durk MR, Garland K, Hanan EJ, Higuchi RI, Hu H, Ly CQ, Paraselli PG, Roberts TC, Schwarz JB, Smith PA, Yu Z, Heise CE. Koehler MFT, et al. Among authors: roberts tc. ACS Med Chem Lett. 2023 Oct 11;14(11):1524-1530. doi: 10.1021/acsmedchemlett.3c00327. eCollection 2023 Nov 9. ACS Med Chem Lett. 2023. PMID: 37974942
Therapeutic approaches for Duchenne muscular dystrophy.
Roberts TC, Wood MJA, Davies KE. Roberts TC, et al. Nat Rev Drug Discov. 2023 Nov;22(11):917-934. doi: 10.1038/s41573-023-00775-6. Epub 2023 Aug 31. Nat Rev Drug Discov. 2023. PMID: 37652974 Review.
Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD.
Hanson B, Stenler S, Ahlskog N, Chwalenia K, Svrzikapa N, Coenen-Stass AML, Weinberg MS, Wood MJA, Roberts TC. Hanson B, et al. Among authors: roberts tc. Mol Ther Nucleic Acids. 2022 Oct 23;30:379-397. doi: 10.1016/j.omtn.2022.10.010. eCollection 2022 Dec 13. Mol Ther Nucleic Acids. 2022. PMID: 36420212 Free PMC article.
Exon skipping induces uniform dystrophin rescue with dose-dependent restoration of serum miRNA biomarkers and muscle biophysical properties.
Chwalenia K, Oieni J, Zemła J, Lekka M, Ahlskog N, Coenen-Stass AML, McClorey G, Wood MJA, Lomonosova Y, Roberts TC. Chwalenia K, et al. Among authors: roberts tc. Mol Ther Nucleic Acids. 2022 Aug 25;29:955-968. doi: 10.1016/j.omtn.2022.08.033. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 36159597 Free PMC article.
AR cooperates with SMAD4 to maintain skeletal muscle homeostasis.
Forouhan M, Lim WF, Zanetti-Domingues LC, Tynan CJ, Roberts TC, Malik B, Manzano R, Speciale AA, Ellerington R, Garcia-Guerra A, Fratta P, Sorarú G, Greensmith L, Pennuto M, Wood MJA, Rinaldi C. Forouhan M, et al. Among authors: roberts tc. Acta Neuropathol. 2022 Jun;143(6):713-731. doi: 10.1007/s00401-022-02428-1. Epub 2022 May 6. Acta Neuropathol. 2022. PMID: 35522298 Free PMC article.
76 results