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332 results

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Page 1
Investigation of genomic and transcriptomic risk factors in clopidogrel response in African Americans.
Yang G, Alarcon C, Chanfreau C, Lee NH, Friedman P, Nutescu E, Tuck M, O'Brien T, Gong L, Klein TE, Chang KM, Tsao PS, Meltzer DO; Million Veteran Program; Tuteja S, Perera MA. Yang G, et al. Among authors: tsao ps. medRxiv [Preprint]. 2023 Dec 7:2023.12.05.23299140. doi: 10.1101/2023.12.05.23299140. medRxiv. 2023. PMID: 38106031 Free PMC article. Preprint.
Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease.
Klarin D, Busenkell E, Judy R, Lynch J, Levin M, Haessler J, Aragam K, Chaffin M, Haas M, Lindström S, Assimes TL, Huang J, Min Lee K, Shao Q, Huffman JE, Kabrhel C, Huang Y, Sun YV, Vujkovic M, Saleheen D, Miller DR, Reaven P, DuVall S, Boden WE, Pyarajan S, Reiner AP, Trégouët DA, Henke P, Kooperberg C, Gaziano JM, Concato J, Rader DJ, Cho K, Chang KM, Wilson PWF, Smith NL, O'Donnell CJ, Tsao PS, Kathiresan S, Obi A, Damrauer SM, Natarajan P; INVENT Consortium; Veterans Affairs’ Million Veteran Program. Klarin D, et al. Among authors: tsao ps. Nat Genet. 2019 Nov;51(11):1574-1579. doi: 10.1038/s41588-019-0519-3. Epub 2019 Nov 1. Nat Genet. 2019. PMID: 31676865 Free PMC article.
Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study.
Hu Y, Graff M, Haessler J, Buyske S, Bien SA, Tao R, Highland HM, Nishimura KK, Zubair N, Lu Y, Verbanck M, Hilliard AT, Klarin D, Damrauer SM, Ho YL; VA Million Veteran Program; Wilson PWF, Chang KM, Tsao PS, Cho K, O'Donnell CJ, Assimes TL, Petty LE, Below JE, Dikilitas O, Schaid DJ, Kosel ML, Kullo IJ, Rasmussen-Torvik LJ, Jarvik GP, Feng Q, Wei WQ, Larson EB, Mentch FD, Almoguera B, Sleiman PM, Raffield LM, Correa A, Martin LW, Daviglus M, Matise TC, Ambite JL, Carlson CS, Do R, Loos RJF, Wilkens LR, Le Marchand L, Haiman C, Stram DO, Hindorff LA, North KE, Kooperberg C, Cheng I, Peters U. Hu Y, et al. Among authors: tsao ps. PLoS Genet. 2020 Mar 30;16(3):e1008684. doi: 10.1371/journal.pgen.1008684. eCollection 2020 Mar. PLoS Genet. 2020. PMID: 32226016 Free PMC article.
Genetic determinants of increased body mass index mediate the effect of smoking on increased risk for type 2 diabetes but not coronary artery disease.
Thom CS, Ding Z, Levin MG, Damrauer SM, Lee KM, Lynch J, Chang KM, Tsao PS, Cho K, Wilson PWF, Assimes TL, Sun YV, O'Donnell CJ; VA Million Veteran Program; Vujkovic M, Voight BF. Thom CS, et al. Among authors: tsao ps. Hum Mol Genet. 2020 Nov 25;29(19):3327-3337. doi: 10.1093/hmg/ddaa193. Hum Mol Genet. 2020. PMID: 32833022 Free PMC article.
Mendelian Randomization Analysis of Hemostatic Factors and Their Contribution to Peripheral Artery Disease-Brief Report.
Small AM, Huffman JE, Klarin D, Sabater-Lleal M, Lynch JA, Assimes TL, Sun YV, Miller D, Freiberg MS, Morrison AC, Rader DJ, Wilson PWF, Cho K, Tsao PS, Chang KM, Smith NL, O'Donnell CJ, de Vries PS, Damrauer SM; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Hemostasis Working Group and the VA Million Veteran Program. Small AM, et al. Among authors: tsao ps. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):380-386. doi: 10.1161/ATVBAHA.119.313847. Epub 2020 Aug 27. Arterioscler Thromb Vasc Biol. 2021. PMID: 32847391 Free PMC article.
PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort.
Small AM, Huffman JE, Klarin D, Lynch JA, Assimes T, DuVall S, Sun YV, Shere L, Natarajan P, Gaziano M, Rader DJ, Wilson PWF, Tsao PS, Chang KM, Cho K, O'Donnell CJ, Casas JP, Damrauer SM; VA Million Veteran Program. Small AM, et al. Among authors: tsao ps. PLoS One. 2020 Nov 9;15(11):e0239752. doi: 10.1371/journal.pone.0239752. eCollection 2020. PLoS One. 2020. PMID: 33166319 Free PMC article.
Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases: A Mendelian Randomization Study.
Levin MG, Klarin D, Assimes TL, Freiberg MS, Ingelsson E, Lynch J, Natarajan P, O'Donnell C, Rader DJ, Tsao PS, Chang KM, Voight BF, Damrauer SM; VA Million Veteran Program. Levin MG, et al. Among authors: tsao ps. JAMA Netw Open. 2021 Jan 4;4(1):e2034461. doi: 10.1001/jamanetworkopen.2020.34461. JAMA Netw Open. 2021. PMID: 33464320 Free PMC article.
Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.
Gaziano L, Giambartolomei C, Pereira AC, Gaulton A, Posner DC, Swanson SA, Ho YL, Iyengar SK, Kosik NM, Vujkovic M, Gagnon DR, Bento AP, Barrio-Hernandez I, Rönnblom L, Hagberg N, Lundtoft C, Langenberg C, Pietzner M, Valentine D, Gustincich S, Tartaglia GG, Allara E, Surendran P, Burgess S, Zhao JH, Peters JE, Prins BP, Angelantonio ED, Devineni P, Shi Y, Lynch KE, DuVall SL, Garcon H, Thomann LO, Zhou JJ, Gorman BR, Huffman JE, O'Donnell CJ, Tsao PS, Beckham JC, Pyarajan S, Muralidhar S, Huang GD, Ramoni R, Beltrao P, Danesh J, Hung AM, Chang KM, Sun YV, Joseph J, Leach AR, Edwards TL, Cho K, Gaziano JM, Butterworth AS, Casas JP; VA Million Veteran Program COVID-19 Science Initiative. Gaziano L, et al. Among authors: tsao ps. Nat Med. 2021 Apr;27(4):668-676. doi: 10.1038/s41591-021-01310-z. Epub 2021 Apr 9. Nat Med. 2021. PMID: 33837377 Free PMC article.
Association Between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease.
Levin MG, Klarin D, Walker VM, Gill D, Lynch J, Hellwege JN, Keaton JM, Lee KM, Assimes TL, Natarajan P, Hung AM, Edwards TL, Rader DJ, Gaziano JM, Davies NM, Tsao PS, Chang KM, Voight BF, Damrauer SM; VA Million Veteran Program. Levin MG, et al. Among authors: tsao ps. Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):2027-2034. doi: 10.1161/ATVBAHA.120.315482. Epub 2021 Apr 15. Arterioscler Thromb Vasc Biol. 2021. PMID: 33853351 Free PMC article.
332 results