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Heightened TLR7 signaling primes BCR-activated B cells in chronic graft-versus-host disease for effector functions.
Bracken SJ, Suthers AN, DiCioccio RA, Su H, Anand S, Poe JC, Jia W, Visentin J, Basher F, Jordan CZ, McManigle WC, Li Z, Hakim FT, Pavletic SZ, Bhuiya NS, Ho VT, Horwitz ME, Chao NJ, Sarantopoulos S. Bracken SJ, et al. Among authors: bhuiya ns. Blood Adv. 2024 Feb 13;8(3):667-680. doi: 10.1182/bloodadvances.2023010362. Blood Adv. 2024. PMID: 38113462 Free PMC article.
B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways.
Allen JL, Fore MS, Wooten J, Roehrs PA, Bhuiya NS, Hoffert T, Sharf A, Deal AM, Armistead P, Coghill J, Gabriel DA, Irons R, Essenmacher A, Shea TC, Richards K, Cutler C, Ritz J, Serody J, Baldwin AS, Sarantopoulos S. Allen JL, et al. Among authors: bhuiya ns. Blood. 2012 Sep 20;120(12):2529-36. doi: 10.1182/blood-2012-06-438911. Epub 2012 Aug 14. Blood. 2012. PMID: 22896003 Free PMC article.
Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease.
Sarantopoulos S, Stevenson KE, Kim HT, Washel WS, Bhuiya NS, Cutler CS, Alyea EP, Ho VT, Soiffer RJ, Antin JH, Ritz J. Sarantopoulos S, et al. Among authors: bhuiya ns. Blood. 2011 Feb 17;117(7):2275-83. doi: 10.1182/blood-2010-10-307819. Epub 2010 Nov 19. Blood. 2011. PMID: 21097674 Free PMC article. Clinical Trial.
Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease.
Sarantopoulos S, Stevenson KE, Kim HT, Cutler CS, Bhuiya NS, Schowalter M, Ho VT, Alyea EP, Koreth J, Blazar BR, Soiffer RJ, Antin JH, Ritz J. Sarantopoulos S, et al. Among authors: bhuiya ns. Blood. 2009 Apr 16;113(16):3865-74. doi: 10.1182/blood-2008-09-177840. Epub 2009 Jan 23. Blood. 2009. PMID: 19168788 Free PMC article.