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Heightened TLR7 signaling primes BCR-activated B cells in chronic graft-versus-host disease for effector functions.
Bracken SJ, Suthers AN, DiCioccio RA, Su H, Anand S, Poe JC, Jia W, Visentin J, Basher F, Jordan CZ, McManigle WC, Li Z, Hakim FT, Pavletic SZ, Bhuiya NS, Ho VT, Horwitz ME, Chao NJ, Sarantopoulos S. Bracken SJ, et al. Among authors: sarantopoulos s. Blood Adv. 2024 Feb 13;8(3):667-680. doi: 10.1182/bloodadvances.2023010362. Blood Adv. 2024. PMID: 38113462 Free PMC article.
Biologic activity of irradiated, autologous, GM-CSF-secreting leukemia cell vaccines early after allogeneic stem cell transplantation.
Ho VT, Vanneman M, Kim H, Sasada T, Kang YJ, Pasek M, Cutler C, Koreth J, Alyea E, Sarantopoulos S, Antin JH, Ritz J, Canning C, Kutok J, Mihm MC, Dranoff G, Soiffer R. Ho VT, et al. Among authors: sarantopoulos s. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15825-30. doi: 10.1073/pnas.0908358106. Epub 2009 Aug 26. Proc Natl Acad Sci U S A. 2009. PMID: 19717467 Free PMC article. Clinical Trial.
B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways.
Allen JL, Fore MS, Wooten J, Roehrs PA, Bhuiya NS, Hoffert T, Sharf A, Deal AM, Armistead P, Coghill J, Gabriel DA, Irons R, Essenmacher A, Shea TC, Richards K, Cutler C, Ritz J, Serody J, Baldwin AS, Sarantopoulos S. Allen JL, et al. Among authors: sarantopoulos s. Blood. 2012 Sep 20;120(12):2529-36. doi: 10.1182/blood-2012-06-438911. Epub 2012 Aug 14. Blood. 2012. PMID: 22896003 Free PMC article.
Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial.
Cutler C, Kim HT, Bindra B, Sarantopoulos S, Ho VT, Chen YB, Rosenblatt J, McDonough S, Watanaboonyongcharoen P, Armand P, Koreth J, Glotzbecker B, Alyea E, Blazar BR, Soiffer RJ, Ritz J, Antin JH. Cutler C, et al. Among authors: sarantopoulos s. Blood. 2013 Aug 22;122(8):1510-7. doi: 10.1182/blood-2013-04-495895. Epub 2013 Jul 16. Blood. 2013. PMID: 23861248 Free PMC article. Clinical Trial.
98 results