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Extrahelical Binding Site for a 1H-Imidazo[4,5-c]quinolin-4-amine A3 Adenosine Receptor Positive Allosteric Modulator on Helix 8 and Distal Portions of Transmembrane Domains 1 and 7.
Fisher CL, Pavan M, Salmaso V, Keyes RF, Wan TC, Pradhan B, Gao ZG, Smith BC, Jacobson KA, Auchampach JA. Fisher CL, et al. Among authors: smith bc. Mol Pharmacol. 2024 Feb 15;105(3):213-223. doi: 10.1124/molpharm.123.000784. Mol Pharmacol. 2024. PMID: 38182432 Free PMC article.
Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types.
Jones Lipinski RA, Stancill JS, Nuñez R, Wynia-Smith SL, Sprague DJ, Nord JA, Bird A, Corbett JA, Smith BC. Jones Lipinski RA, et al. Among authors: smith bc. Am J Physiol Regul Integr Comp Physiol. 2024 Jun 1;326(6):R515-R527. doi: 10.1152/ajpregu.00259.2023. Epub 2024 Apr 15. Am J Physiol Regul Integr Comp Physiol. 2024. PMID: 38618911
Fragment-based screening by protein-detected NMR spectroscopy.
Kerber PJ, Nuñez R, Jensen DR, Zhou AL, Peterson FC, Hill RB, Volkman BF, Smith BC. Kerber PJ, et al. Among authors: smith bc. Methods Enzymol. 2023;690:285-310. doi: 10.1016/bs.mie.2023.06.018. Epub 2023 Jul 29. Methods Enzymol. 2023. PMID: 37858532
Analysis of continuous enzyme kinetic data using ICEKAT.
Bursch KL, Olp MD, Smith BC. Bursch KL, et al. Among authors: smith bc. Methods Enzymol. 2023;690:109-129. doi: 10.1016/bs.mie.2023.06.019. Epub 2023 Jul 29. Methods Enzymol. 2023. PMID: 37858527
Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.
Ratnasinghe BD, Haque N, Wagenknecht JB, Jensen DR, Esparza GV, Leverence EN, De Assuncao TM, Mathison AJ, Lomberk G, Smith BC, Volkman BF, Urrutia R, Zimmermann MT. Ratnasinghe BD, et al. Among authors: smith bc. bioRxiv [Preprint]. 2023 Apr 28:2023.04.28.536249. doi: 10.1101/2023.04.28.536249. bioRxiv. 2023. PMID: 37207265 Free PMC article. Updated. Preprint.
308 results