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Stress-induced mucin 13 reductions drive intestinal microbiome shifts and despair behaviors.
Rivet-Noor CR, Merchak AR, Render C, Gay NM, Beiter RM, Brown RM, Keeler A, Moreau GB, Li S, Olgun DG, Steigmeyer AD, Ofer R, Phan T, Vemuri K, Chen L, Mahoney KE, Shin JB, Malaker SA, Deppmann C, Verzi MP, Gaultier A. Rivet-Noor CR, et al. Among authors: malaker sa. Brain Behav Immun. 2024 Apr 4;119:665-680. doi: 10.1016/j.bbi.2024.03.028. Online ahead of print. Brain Behav Immun. 2024. PMID: 38579936 Free article.
Optimized mucin-selective enrichment strategy to probe the mucinome.
Mahoney KE, Chang V, Lucas TM, Maruszko K, Malaker SA. Mahoney KE, et al. Among authors: malaker sa. bioRxiv [Preprint]. 2023 Dec 18:2023.12.18.572204. doi: 10.1101/2023.12.18.572204. bioRxiv. 2023. PMID: 38187615 Free PMC article. Updated. Preprint.
Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE.
Chongsaritsinsuk J, Steigmeyer AD, Mahoney KE, Rosenfeld MA, Lucas TM, Smith CM, Li A, Ince D, Kearns FL, Battison AS, Hollenhorst MA, Judy Shon D, Tiemeyer KH, Attah V, Kwon C, Bertozzi CR, Ferracane MJ, Lemmon MA, Amaro RE, Malaker SA. Chongsaritsinsuk J, et al. Among authors: malaker sa. Nat Commun. 2023 Oct 4;14(1):6169. doi: 10.1038/s41467-023-41756-y. Nat Commun. 2023. PMID: 37794035 Free PMC article.
False-Positive Glycopeptide Identification via In-FAIMS Fragmentation.
Rangel-Angarita V, Mahoney KE, Kwon C, Sarker R, Lucas TM, Malaker SA. Rangel-Angarita V, et al. Among authors: malaker sa. JACS Au. 2023 Sep 12;3(9):2498-2509. doi: 10.1021/jacsau.3c00264. eCollection 2023 Sep 25. JACS Au. 2023. PMID: 37772174 Free PMC article.
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Pedram K, et al. Among authors: malaker sa. Nat Biotechnol. 2024 Apr;42(4):597-607. doi: 10.1038/s41587-023-01840-6. Epub 2023 Aug 3. Nat Biotechnol. 2024. PMID: 37537499 Free PMC article.
Vibrio cholerae biofilms use modular adhesins with glycan-targeting and nonspecific surface binding domains for colonization.
Huang X, Nero T, Weerasekera R, Matej KH, Hinbest A, Jiang Z, Lee RF, Wu L, Chak C, Nijjer J, Gibaldi I, Yang H, Gamble N, Ng WL, Malaker SA, Sumigray K, Olson R, Yan J. Huang X, et al. Among authors: malaker sa. Nat Commun. 2023 Apr 13;14(1):2104. doi: 10.1038/s41467-023-37660-0. Nat Commun. 2023. PMID: 37055389 Free PMC article.
O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern.
Gonzalez-Rodriguez E, Zol-Hanlon M, Bineva-Todd G, Marchesi A, Skehel M, Mahoney KE, Roustan C, Borg A, Di Vagno L, Kjær S, Wrobel AG, Benton DJ, Nawrath P, Flitsch SL, Joshi D, González-Ramírez AM, Wilkinson KA, Wilkinson RJ, Wall EC, Hurtado-Guerrero R, Malaker SA, Schumann B. Gonzalez-Rodriguez E, et al. Among authors: malaker sa. ACS Cent Sci. 2023 Feb 16;9(3):393-404. doi: 10.1021/acscentsci.2c01349. eCollection 2023 Mar 22. ACS Cent Sci. 2023. PMID: 36968546 Free PMC article.
46 results