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Differential microRNA editing may drive target pathway switching in human temporal lobe epilepsy.
Brain Commun. 2024 Jan 3;6(1):fcad355. doi: 10.1093/braincomms/fcad355. eCollection 2024.
Brain Commun. 2024.
PMID: 38204971
Free PMC article.
AntimiR targeting of microRNA-134 reduces seizures in a mouse model of Angelman syndrome.
Campbell A, Morris G, Sanfeliu A, Augusto J, Langa E, Kesavan JC, Nguyen NT, Conroy RM, Worm J, Kielpinski L, Jensen MA, Miller MT, Kremer T, Reschke CR, Henshall DC.
Campbell A, et al. Among authors: kesavan jc.
Mol Ther Nucleic Acids. 2022 Apr 20;28:514-529. doi: 10.1016/j.omtn.2022.04.009. eCollection 2022 Jun 14.
Mol Ther Nucleic Acids. 2022.
PMID: 35592499
Free PMC article.
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Functional expression of the ATP-gated P2X7 receptor in human iPSC-derived astrocytes.
Kesavan J, Watters O, de Diego-Garcia L, Méndez AM, Alves M, Dinkel K, Hamacher M, Prehn JHM, Henshall DC, Engel T.
Kesavan J, et al.
Purinergic Signal. 2023 Jul 15. doi: 10.1007/s11302-023-09957-8. Online ahead of print.
Purinergic Signal. 2023.
PMID: 37453017
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MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control.
Heiland M, Connolly NMC, Mamad O, Nguyen NT, Kesavan JC, Langa E, Fanning K, Sanfeliu A, Yan Y, Su J, Venø MT, Costard LS, Neubert V, Engel T, Hill TDM, Freiman TM, Mahesh A, Tiwari VK, Rosenow F, Bauer S, Kjems J, Morris G, Henshall DC.
Heiland M, et al. Among authors: kesavan jc.
Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2216658120. doi: 10.1073/pnas.2216658120. Epub 2023 Jul 18.
Proc Natl Acad Sci U S A. 2023.
PMID: 37463203
Free PMC article.
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Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice.
Alves M, Gil B, Villegas-Salmerón J, Salari V, Martins-Ferreira R, Arribas Blázquez M, Menéndez Méndez A, Da Rosa Gerbatin R, Smith J, de Diego-Garcia L, Conte G, Sierra-Marquez J, Merino Serrais P, Mitra M, Fernandez Martin A, Wang Y, Kesavan J, Melia C, Parras A, Beamer E, Zimmer B, Heiland M, Cavanagh B, Parcianello Cipolat R, Morgan J, Teng X, Prehn JHM, Fabene PF, Bertini G, Artalejo AR, Ballestar E, Nicke A, Olivos-Oré LA, Connolly NMC, Henshall DC, Engel T.
Alves M, et al.
Brain Behav Immun. 2024 May 20;120:121-140. doi: 10.1016/j.bbi.2024.05.023. Online ahead of print.
Brain Behav Immun. 2024.
PMID: 38777288
Free article.
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APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.
Mertens J, Stüber K, Wunderlich P, Ladewig J, Kesavan JC, Vandenberghe R, Vandenbulcke M, van Damme P, Walter J, Brüstle O, Koch P.
Mertens J, et al. Among authors: kesavan jc.
Stem Cell Reports. 2013 Dec 5;1(6):491-8. doi: 10.1016/j.stemcr.2013.10.011. eCollection 2013.
Stem Cell Reports. 2013.
PMID: 24371804
Free PMC article.
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