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Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer.
Pfeifer M, Brammeld JS, Price S, Pilling J, Bhavsar D, Farcas A, Bateson J, Sundarrajan A, Miragaia RJ, Guan N, Arnold S, Tariq L, Grondine M, Talbot S, Guerriero ML, O'Neill DJ, Young J, Company C, Dunn S, Thorpe H, Martin MJ, Maratea K, Barrell D, Ahdesmaki M, Mettetal JT; Functional Genomics Centre; Brownell J, McDermott U. Pfeifer M, et al. Among authors: thorpe h. Commun Biol. 2024 Apr 24;7(1):497. doi: 10.1038/s42003-024-06190-w. Commun Biol. 2024. PMID: 38658677 Free PMC article.
Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking.
Johnson EC, Austin-Zimmerman I, Thorpe HH, Levey DF, Baranger DA, Colbert SM, Demontis D, Khokhar JY, Davis LK, Edenberg HJ, Forti MD, Sanchez-Roige S, Gelernter J, Agrawal A. Johnson EC, et al. Among authors: thorpe hh. medRxiv [Preprint]. 2024 Jan 18:2024.01.17.24301430. doi: 10.1101/2024.01.17.24301430. medRxiv. 2024. PMID: 38293235 Free PMC article. Preprint.
Drosophila models of PIGA-CDG mirror patient phenotypes.
Thorpe HJ, Owings KG, Aziz MC, Haller M, Coelho E, Chow CY. Thorpe HJ, et al. bioRxiv [Preprint]. 2023 Oct 27:2023.10.27.564441. doi: 10.1101/2023.10.27.564441. bioRxiv. 2023. PMID: 37961693 Free PMC article. Updated. Preprint.
Population structure and antimicrobial resistance among Klebsiella isolates sampled from human, animal, and environmental sources in Ghana: a cross-sectional genomic One Health study.
Calland JK, Haukka K, Kpordze SW, Brusah A, Corbella M, Merla C, Samuelsen Ø, Feil EJ, Sassera D, Karikari AB, Saba CKS, Thorpe HA, Corander J. Calland JK, et al. Among authors: thorpe ha. Lancet Microbe. 2023 Nov;4(11):e943-e952. doi: 10.1016/S2666-5247(23)00208-2. Epub 2023 Oct 16. Lancet Microbe. 2023. PMID: 37858320 Free article.
Genome-Wide Association Studies of Coffee Intake in UK/US Participants of European Ancestry Uncover Gene-Cohort Influences.
Thorpe HHA, Fontanillas P, Pham BK, Meredith JJ, Jennings MV, Courchesne-Krak NS, Vilar-Ribó L, Bianchi SB, Mutz J; 23andMe Research Team; Elson SL, Khokhar JY, Abdellaoui A, Davis LK, Palmer AA, Sanchez-Roige S. Thorpe HHA, et al. medRxiv [Preprint]. 2023 Sep 11:2023.09.09.23295284. doi: 10.1101/2023.09.09.23295284. medRxiv. 2023. PMID: 37745582 Free PMC article. Preprint.
CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice.
Sanchez-Roige S, Jennings MV, Thorpe HHA, Mallari JE, van der Werf LC, Bianchi SB, Huang Y, Lee C, Mallard TT, Barnes SA, Wu JY, Barkley-Levenson AM, Boussaty EC, Snethlage CE, Schafer D, Babic Z, Winters BD, Watters KE, Biederer T; 23andMe Research Team; Mackillop J, Stephens DN, Elson SL, Fontanillas P, Khokhar JY, Young JW, Palmer AA. Sanchez-Roige S, et al. Among authors: thorpe hha. Transl Psychiatry. 2023 May 12;13(1):167. doi: 10.1038/s41398-023-02453-y. Transl Psychiatry. 2023. PMID: 37173343 Free PMC article.
156 results