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Page 1
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies.
Martin-Alonso C, Tabrizi S, Xiong K, Blewett T, Sridhar S, Crnjac A, Patel S, An Z, Bekdemir A, Shea D, Wang ST, Rodriguez-Aponte S, Naranjo CA, Rhoades J, Kirkpatrick JD, Fleming HE, Amini AP, Golub TR, Love JC, Bhatia SN, Adalsteinsson VA. Martin-Alonso C, et al. Among authors: golub tr. Science. 2024 Jan 19;383(6680):eadf2341. doi: 10.1126/science.adf2341. Epub 2024 Jan 19. Science. 2024. PMID: 38236959
Duplex-Repair enables highly accurate sequencing, despite DNA damage.
Xiong K, Shea D, Rhoades J, Blewett T, Liu R, Bae JH, Nguyen E, Makrigiorgos GM, Golub TR, Adalsteinsson VA. Xiong K, et al. Among authors: golub tr. Nucleic Acids Res. 2022 Jan 11;50(1):e1. doi: 10.1093/nar/gkab855. Nucleic Acids Res. 2022. PMID: 34591958 Free PMC article.
Liquid biopsy detection of genomic alterations in pediatric brain tumors from cell-free DNA in peripheral blood, CSF, and urine.
Pagès M, Rotem D, Gydush G, Reed S, Rhoades J, Ha G, Lo C, Fleharty M, Duran M, Jones R, Becker S, Haller M, Sinai CE, Goumnerova L, Golub TR, Love JC, Ligon KL, Wright KD, Adalsteinsson VA, Beroukhim R, Bandopadhayay P. Pagès M, et al. Among authors: golub tr. Neuro Oncol. 2022 Aug 1;24(8):1352-1363. doi: 10.1093/neuonc/noab299. Neuro Oncol. 2022. PMID: 34984433 Free PMC article.
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity.
Bae JH, Liu R, Roberts E, Nguyen E, Tabrizi S, Rhoades J, Blewett T, Xiong K, Gydush G, Shea D, An Z, Patel S, Cheng J, Sridhar S, Liu MH, Lassen E, Skytte AB, Grońska-Pęski M, Shoag JE, Evrony GD, Parsons HA, Mayer EL, Makrigiorgos GM, Golub TR, Adalsteinsson VA. Bae JH, et al. Among authors: golub tr. Nat Genet. 2023 May;55(5):871-879. doi: 10.1038/s41588-023-01376-0. Epub 2023 Apr 27. Nat Genet. 2023. PMID: 37106072 Free PMC article.
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.
Adalsteinsson VA, Ha G, Freeman SS, Choudhury AD, Stover DG, Parsons HA, Gydush G, Reed SC, Rotem D, Rhoades J, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Kim J, Stewart C, Rosenberg M, Francis JM, Zhang CZ, Cohen O, Oh C, Ding H, Polak P, Lloyd M, Mahmud S, Helvie K, Merrill MS, Santiago RA, O'Connor EP, Jeong SH, Leeson R, Barry RM, Kramkowski JF, Zhang Z, Polacek L, Lohr JG, Schleicher M, Lipscomb E, Saltzman A, Oliver NM, Marini L, Waks AG, Harshman LC, Tolaney SM, Van Allen EM, Winer EP, Lin NU, Nakabayashi M, Taplin ME, Johannessen CM, Garraway LA, Golub TR, Boehm JS, Wagle N, Getz G, Love JC, Meyerson M. Adalsteinsson VA, et al. Among authors: golub tr. Nat Commun. 2017 Nov 6;8(1):1324. doi: 10.1038/s41467-017-00965-y. Nat Commun. 2017. PMID: 29109393 Free PMC article.
Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth.
Gydush G, Nguyen E, Bae JH, Blewett T, Rhoades J, Reed SC, Shea D, Xiong K, Liu R, Yu F, Leong KW, Choudhury AD, Stover DG, Tolaney SM, Krop IE, Christopher Love J, Parsons HA, Mike Makrigiorgos G, Golub TR, Adalsteinsson VA. Gydush G, et al. Among authors: golub tr. Nat Biomed Eng. 2022 Mar;6(3):257-266. doi: 10.1038/s41551-022-00855-9. Epub 2022 Mar 17. Nat Biomed Eng. 2022. PMID: 35301450 Free PMC article.
Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer.
Stover DG, Parsons HA, Ha G, Freeman SS, Barry WT, Guo H, Choudhury AD, Gydush G, Reed SC, Rhoades J, Rotem D, Hughes ME, Dillon DA, Partridge AH, Wagle N, Krop IE, Getz G, Golub TR, Love JC, Winer EP, Tolaney SM, Lin NU, Adalsteinsson VA. Stover DG, et al. Among authors: golub tr. J Clin Oncol. 2018 Feb 20;36(6):543-553. doi: 10.1200/JCO.2017.76.0033. Epub 2018 Jan 3. J Clin Oncol. 2018. PMID: 29298117 Free PMC article.
Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer.
Parsons HA, Rhoades J, Reed SC, Gydush G, Ram P, Exman P, Xiong K, Lo CC, Li T, Fleharty M, Kirkner GJ, Rotem D, Cohen O, Yu F, Fitarelli-Kiehl M, Leong KW, Hughes ME, Rosenberg SM, Collins LC, Miller KD, Blumenstiel B, Trippa L, Cibulskis C, Neuberg DS, DeFelice M, Freeman SS, Lennon NJ, Wagle N, Ha G, Stover DG, Choudhury AD, Getz G, Winer EP, Meyerson M, Lin NU, Krop I, Love JC, Makrigiorgos GM, Partridge AH, Mayer EL, Golub TR, Adalsteinsson VA. Parsons HA, et al. Among authors: golub tr. Clin Cancer Res. 2020 Jun 1;26(11):2556-2564. doi: 10.1158/1078-0432.CCR-19-3005. Epub 2020 Mar 13. Clin Cancer Res. 2020. PMID: 32170028 Free PMC article.
Circulating tumor DNA association with residual cancer burden after neoadjuvant chemotherapy in triple-negative breast cancer in TBCRC 030.
Parsons HA, Blewett T, Chu X, Sridhar S, Santos K, Xiong K, Abramson VG, Patel A, Cheng J, Brufsky A, Rhoades J, Force J, Liu R, Traina TA, Carey LA, Rimawi MF, Miller KD, Stearns V, Specht J, Falkson C, Burstein HJ, Wolff AC, Winer EP, Tayob N, Krop IE, Makrigiorgos GM, Golub TR, Mayer EL, Adalsteinsson VA. Parsons HA, et al. Among authors: golub tr. Ann Oncol. 2023 Oct;34(10):899-906. doi: 10.1016/j.annonc.2023.08.004. Epub 2023 Aug 18. Ann Oncol. 2023. PMID: 37597579 Free article.
Humanized mice with ectopic artificial liver tissues.
Chen AA, Thomas DK, Ong LL, Schwartz RE, Golub TR, Bhatia SN. Chen AA, et al. Among authors: golub tr. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11842-7. doi: 10.1073/pnas.1101791108. Epub 2011 Jul 11. Proc Natl Acad Sci U S A. 2011. PMID: 21746904 Free PMC article.
288 results