Chacko SA - Search Results

1

Effectiveness of Swallowing and Oral Care Interventions on Oral Intake and Salivary Flow of Patients Following Endotracheal Extubation at a Tertiary Care Center: A Randomized Controlled Trial.

Chacko SA, Ramamoorthy L, Cherian A, Anusuya R, Lalthanthuami HT, Subramaniyan R. Chacko SA, et al. J Caring Sci. 2023 Nov 12;12(4):213-220. doi: 10.34172/jcs.2023.33005. eCollection 2023 Dec. J Caring Sci. 2023. PMID: 38250001 Free PMC article.

2

The Current Status and Use of Microphysiological Systems by the Pharmaceutical Industry: The International Consortium for Innovation and Quality Microphysiological Systems Affiliate Survey and Commentary.

Baker TK, Van Vleet TR, Mahalingaiah PK, Grandhi TSP, Evers R, Ekert J, Gosset JR, Chacko SA, Kopec AK. Baker TK, et al. Among authors: chacko sa. Drug Metab Dispos. 2024 Feb 14;52(3):198-209. doi: 10.1124/dmd.123.001510. Drug Metab Dispos. 2024. PMID: 38123948

3

Preclinical metabolism and disposition of an orally bioavailable macrocyclic FXIa inhibitor.

Chacko SA, Yang W, Wang Y, Tian Y, Hong Y, Wallace M, Wang B, Ewing WR, Luettgen JM, Shu YZ, Christopher LJ. Chacko SA, et al. Xenobiotica. 2021 Aug;51(8):933-948. doi: 10.1080/00498254.2021.1943565. Epub 2021 Jul 5. Xenobiotica. 2021. PMID: 34151691

4

Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species.

Yang W, Wang Y, Lai A, Clark CG, Corte JR, Fang T, Gilligan PJ, Jeon Y, Pabbisetty KB, Rampulla RA, Mathur A, Kaspady M, Neithnadka PR, Arumugam A, Raju S, Rossi KA, Myers JE Jr, Sheriff S, Lou Z, Zheng JJ, Chacko SA, Bozarth JM, Wu Y, Crain EJ, Wong PC, Seiffert DA, Luettgen JM, Lam PYS, Wexler RR, Ewing WR. Yang W, et al. Among authors: chacko sa. J Med Chem. 2020 Jul 9;63(13):7226-7242. doi: 10.1021/acs.jmedchem.0c00464. Epub 2020 Jun 17. J Med Chem. 2020. PMID: 32456431

5

Hepatocyte spheroids as a viable in vitro model for recapitulation of complex in vivo metabolism pathways of loratadine in humans.

Chacko SA, Ly VT, Christopher LJ, Gan J. Chacko SA, et al. Xenobiotica. 2020 Jun;50(6):621-629. doi: 10.1080/00498254.2019.1675100. Epub 2019 Oct 10. Xenobiotica. 2020. PMID: 31566996

6

Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212).

Pinto DJP, Orwat MJ, Smith LM 2nd, Quan ML, Lam PYS, Rossi KA, Apedo A, Bozarth JM, Wu Y, Zheng JJ, Xin B, Toussaint N, Stetsko P, Gudmundsson O, Maxwell B, Crain EJ, Wong PC, Lou Z, Harper TW, Chacko SA, Myers JE Jr, Sheriff S, Zhang H, Hou X, Mathur A, Seiffert DA, Wexler RR, Luettgen JM, Ewing WR. Pinto DJP, et al. Among authors: chacko sa. J Med Chem. 2017 Dec 14;60(23):9703-9723. doi: 10.1021/acs.jmedchem.7b01171. Epub 2017 Nov 17. J Med Chem. 2017. PMID: 29077405

7

A mindfulness-based intervention to control weight after bariatric surgery: Preliminary results from a randomized controlled pilot trial.

Chacko SA, Yeh GY, Davis RB, Wee CC. Chacko SA, et al. Complement Ther Med. 2016 Oct;28:13-21. doi: 10.1016/j.ctim.2016.07.001. Epub 2016 Jul 12. Complement Ther Med. 2016. PMID: 27670865 Free PMC article. Clinical Trial.

8

Genetic variations in magnesium-related ion channels may affect diabetes risk among African American and Hispanic American women.

Chan KH, Chacko SA, Song Y, Cho M, Eaton CB, Wu WC, Liu S. Chan KH, et al. Among authors: chacko sa. J Nutr. 2015 Mar;145(3):418-24. doi: 10.3945/jn.114.203489. Epub 2015 Jan 7. J Nutr. 2015. PMID: 25733456 Free PMC article.

9

Recognizing disordered eating in primary care patients with obesity.

Chacko SA, Chiodi SN, Wee CC. Chacko SA, et al. Prev Med. 2015 Mar;72:89-94. doi: 10.1016/j.ypmed.2014.12.024. Epub 2015 Jan 5. Prev Med. 2015. PMID: 25572624 Free PMC article.

10

4-Benzothiazole-7-hydroxyindolinyl diaryl ureas are potent P2Y1 antagonists with favorable pharmacokinetics: low clearance and small volume of distribution.

Qiao JX, Wang TC, Hiebert S, Hu CH, Schumacher WA, Spronk SA, Clark CG, Han Y, Hua J, Price LA, Shen H, Chacko SA, Everlof G, Bostwick JS, Steinbacher TE, Li YX, Huang CS, Seiffert DA, Rehfuss R, Wexler RR, Lam PY. Qiao JX, et al. Among authors: chacko sa. ChemMedChem. 2014 Oct;9(10):2327-43. doi: 10.1002/cmdc.201402141. Epub 2014 Jul 2. ChemMedChem. 2014. PMID: 24989964

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