Boucher D - Search Results

1

NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome.

Coombs JR, Zamoshnikova A, Holley CL, Maddugoda MP, Teo DET, Chauvin C, Poulin LF, Vitak N, Ross CM, Mellacheruvu M, Coll RC, Heinz LX, Burgener SS, Emming S, Chamaillard M, Boucher D, Schroder K. Coombs JR, et al. Among authors: boucher d. Sci Signal. 2024 Jan 23;17(820):eabg8145. doi: 10.1126/scisignal.abg8145. Epub 2024 Jan 23. Sci Signal. 2024. PMID: 38261657

2

Salmonella-induced inflammasome activation in humans.

Bierschenk D, Boucher D, Schroder K. Bierschenk D, et al. Among authors: boucher d. Mol Immunol. 2017 Jun;86:38-43. doi: 10.1016/j.molimm.2016.11.009. Epub 2016 Dec 11. Mol Immunol. 2017. PMID: 27974148 Review.

3

Quantifying Caspase-1 Activity in Murine Macrophages.

Boucher D, Chan A, Ross C, Schroder K. Boucher D, et al. Methods Mol Biol. 2018;1725:163-176. doi: 10.1007/978-1-4939-7568-6_14. Methods Mol Biol. 2018. PMID: 29322417

4

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.

Boucher D, Monteleone M, Coll RC, Chen KW, Ross CM, Teo JL, Gomez GA, Holley CL, Bierschenk D, Stacey KJ, Yap AS, Bezbradica JS, Schroder K. Boucher D, et al. J Exp Med. 2018 Mar 5;215(3):827-840. doi: 10.1084/jem.20172222. Epub 2018 Feb 6. J Exp Med. 2018. PMID: 29432122 Free PMC article.

5

The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses.

Bierschenk D, Monteleone M, Moghaddas F, Baker PJ, Masters SL, Boucher D, Schroder K. Bierschenk D, et al. Among authors: boucher d. J Leukoc Biol. 2019 Feb;105(2):401-410. doi: 10.1002/JLB.MA0318-112RR. Epub 2018 Oct 4. J Leukoc Biol. 2019. PMID: 30368901

6

Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome.

Ross C, Chan AH, Von Pein J, Boucher D, Schroder K. Ross C, et al. Among authors: boucher d. Life Sci Alliance. 2018 Dec 6;1(6):e201800237. doi: 10.26508/lsa.201800237. eCollection 2018 Dec. Life Sci Alliance. 2018. PMID: 30564782 Free PMC article.

7

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.

Coll RC, Hill JR, Day CJ, Zamoshnikova A, Boucher D, Massey NL, Chitty JL, Fraser JA, Jennings MP, Robertson AAB, Schroder K. Coll RC, et al. Among authors: boucher d. Nat Chem Biol. 2019 Jun;15(6):556-559. doi: 10.1038/s41589-019-0277-7. Epub 2019 May 13. Nat Chem Biol. 2019. PMID: 31086327

8

Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes.

Ross C, Chan AH, von Pein JB, Maddugoda MP, Boucher D, Schroder K. Ross C, et al. Among authors: boucher d. Annu Rev Immunol. 2022 Apr 26;40:249-269. doi: 10.1146/annurev-immunol-101220-030653. Epub 2022 Jan 26. Annu Rev Immunol. 2022. PMID: 35080918 Review.

9

Activation of the Non-canonical Inflammasome in Mouse and Human Cells.

Bezbradica JS, Coll RC, Boucher D. Bezbradica JS, et al. Among authors: boucher d. Methods Mol Biol. 2022;2459:51-63. doi: 10.1007/978-1-0716-2144-8_5. Methods Mol Biol. 2022. PMID: 35212953

10

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.

Baker PJ, Boucher D, Bierschenk D, Tebartz C, Whitney PG, D'Silva DB, Tanzer MC, Monteleone M, Robertson AA, Cooper MA, Alvarez-Diaz S, Herold MJ, Bedoui S, Schroder K, Masters SL. Baker PJ, et al. Among authors: d silva db, boucher d. Eur J Immunol. 2015 Oct;45(10):2918-26. doi: 10.1002/eji.201545655. Epub 2015 Aug 24. Eur J Immunol. 2015. PMID: 26173988 Free article.

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