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NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome.
Coombs JR, Zamoshnikova A, Holley CL, Maddugoda MP, Teo DET, Chauvin C, Poulin LF, Vitak N, Ross CM, Mellacheruvu M, Coll RC, Heinz LX, Burgener SS, Emming S, Chamaillard M, Boucher D, Schroder K. Coombs JR, et al. Among authors: chamaillard m. Sci Signal. 2024 Jan 23;17(820):eabg8145. doi: 10.1126/scisignal.abg8145. Epub 2024 Jan 23. Sci Signal. 2024. PMID: 38261657
Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation.
Madouri F, Guillou N, Fauconnier L, Marchiol T, Rouxel N, Chenuet P, Ledru A, Apetoh L, Ghiringhelli F, Chamaillard M, Zheng SG, Trovero F, Quesniaux VF, Ryffel B, Togbe D. Madouri F, et al. Among authors: chamaillard m. J Mol Cell Biol. 2015 Aug;7(4):351-65. doi: 10.1093/jmcb/mjv012. Epub 2015 Feb 24. J Mol Cell Biol. 2015. PMID: 25714839
Keeping the (S)toolbox Alive Outside of the Body for Drugs Discovery.
Poulin LF, Peyrin-Biroulet L, Collard D, Chamaillard M. Poulin LF, et al. Among authors: chamaillard m. Gastroenterology. 2017 Dec;153(6):1689-1691. doi: 10.1053/j.gastro.2017.10.022. Epub 2017 Oct 31. Gastroenterology. 2017. PMID: 29100849 No abstract available.
A dietary flavone confers communicable protection against colitis through NLRP6 signaling independently of inflammasome activation.
Radulovic K, Normand S, Rehman A, Delanoye-Crespin A, Chatagnon J, Delacre M, Waldschmitt N, Poulin LF, Iovanna J, Ryffel B, Rosenstiel P, Chamaillard M. Radulovic K, et al. Among authors: chamaillard m. Mucosal Immunol. 2018 May;11(3):811-819. doi: 10.1038/mi.2017.87. Epub 2017 Nov 15. Mucosal Immunol. 2018. PMID: 29139477 Free article.
The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure.
Waldschmitt N, Kitamoto S, Secher T, Zacharioudaki V, Boulard O, Floquet E, Delacre M, Lamas B, Pham HP, Six A, Richard ML, Dagorn JC, Eberl G, Langella P, Chatel JM, Ryffel B, Iovanna JL, Poulin LF, Sokol H, Kamada N, Chamaillard M. Waldschmitt N, et al. Among authors: chamaillard m. Gut. 2019 Jul;68(7):1190-1199. doi: 10.1136/gutjnl-2018-316757. Epub 2018 Oct 2. Gut. 2019. PMID: 30279238
Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens.
Normand S, Waldschmitt N, Neerincx A, Martinez-Torres RJ, Chauvin C, Couturier-Maillard A, Boulard O, Cobret L, Awad F, Huot L, Ribeiro-Ribeiro A, Lautz K, Ruez R, Delacre M, Bondu C, Guilliams M, Scott C, Segal A, Amselem S, Hot D, Karabina S, Bohn E, Ryffel B, Poulin LF, Kufer TA, Chamaillard M. Normand S, et al. Among authors: chamaillard m. Nat Commun. 2018 Dec 17;9(1):5338. doi: 10.1038/s41467-018-07750-5. Nat Commun. 2018. PMID: 30559449 Free PMC article.
144 results