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NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome.
Sci Signal. 2024 Jan 23;17(820):eabg8145. doi: 10.1126/scisignal.abg8145. Epub 2024 Jan 23.
Sci Signal. 2024.
PMID: 38261657
Reversing the mitochondrial hex that bewitches NLRP3.
Mellacheruvu M, Lawrence GMEP, Emming S, Schroder K.
Mellacheruvu M, et al.
Sci Immunol. 2023 Jun 23;8(84):eadh2967. doi: 10.1126/sciimmunol.adh2967. Epub 2023 Jun 16.
Sci Immunol. 2023.
PMID: 37327323
Review.
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The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis.
Holley CL, Emming S, Monteleone MM, Mellacheruvu M, Kenney KM, Lawrence GMEP, Coombs JR, Burgener SS, Schroder K.
Holley CL, et al. Among authors: mellacheruvu m.
Cell Chem Biol. 2024 May 16;31(5):962-972.e4. doi: 10.1016/j.chembiol.2024.04.012.
Cell Chem Biol. 2024.
PMID: 38759620
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