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NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome.
Coombs JR, Zamoshnikova A, Holley CL, Maddugoda MP, Teo DET, Chauvin C, Poulin LF, Vitak N, Ross CM, Mellacheruvu M, Coll RC, Heinz LX, Burgener SS, Emming S, Chamaillard M, Boucher D, Schroder K. Coombs JR, et al. Among authors: poulin lf. Sci Signal. 2024 Jan 23;17(820):eabg8145. doi: 10.1126/scisignal.abg8145. Epub 2024 Jan 23. Sci Signal. 2024. PMID: 38261657
Loss of NOD2 in macrophages improves colitis and tumorigenesis in a lysozyme-dependent manner.
Chauvin C, Radulovic K, Boulard O, Delacre M, Waldschmitt N, Régnier P, Legris G, Bouchez C, Sleimi MY, Rosenstiel P, Darrasse-Jèze G, Chamaillard M, Poulin LF. Chauvin C, et al. Among authors: poulin lf. Front Immunol. 2023 Oct 9;14:1252979. doi: 10.3389/fimmu.2023.1252979. eCollection 2023. Front Immunol. 2023. PMID: 37876927 Free PMC article.
NOD2 in monocytes negatively regulates macrophage development through TNFalpha.
Chauvin C, Alvarez-Simon D, Radulovic K, Boulard O, Laine W, Delacre M, Waldschmitt N, Segura E, Kluza J, Chamaillard M, Poulin LF. Chauvin C, et al. Among authors: poulin lf. Front Immunol. 2023 Jun 21;14:1181823. doi: 10.3389/fimmu.2023.1181823. eCollection 2023. Front Immunol. 2023. PMID: 37415975 Free PMC article.
Activation of Nod2 signaling upon norovirus infection enhances antiviral immunity and susceptibility to colitis.
Muharram G, Thépaut M, Lobert PE, Grandjean T, Boulard O, Delacre M, Wakeford E, Wheeler R, Poulin LF, Boneca IG, Lafont F, Michallet MC, Hober D, Cadwell K, Chamaillard M. Muharram G, et al. Among authors: poulin lf. Gut Microbes. 2023 Dec;15(2):2249960. doi: 10.1080/19490976.2023.2249960. Gut Microbes. 2023. PMID: 37655966 Free PMC article.
Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens.
Normand S, Waldschmitt N, Neerincx A, Martinez-Torres RJ, Chauvin C, Couturier-Maillard A, Boulard O, Cobret L, Awad F, Huot L, Ribeiro-Ribeiro A, Lautz K, Ruez R, Delacre M, Bondu C, Guilliams M, Scott C, Segal A, Amselem S, Hot D, Karabina S, Bohn E, Ryffel B, Poulin LF, Kufer TA, Chamaillard M. Normand S, et al. Among authors: poulin lf. Nat Commun. 2018 Dec 17;9(1):5338. doi: 10.1038/s41467-018-07750-5. Nat Commun. 2018. PMID: 30559449 Free PMC article.
The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure.
Waldschmitt N, Kitamoto S, Secher T, Zacharioudaki V, Boulard O, Floquet E, Delacre M, Lamas B, Pham HP, Six A, Richard ML, Dagorn JC, Eberl G, Langella P, Chatel JM, Ryffel B, Iovanna JL, Poulin LF, Sokol H, Kamada N, Chamaillard M. Waldschmitt N, et al. Among authors: poulin lf. Gut. 2019 Jul;68(7):1190-1199. doi: 10.1136/gutjnl-2018-316757. Epub 2018 Oct 2. Gut. 2019. PMID: 30279238
A dietary flavone confers communicable protection against colitis through NLRP6 signaling independently of inflammasome activation.
Radulovic K, Normand S, Rehman A, Delanoye-Crespin A, Chatagnon J, Delacre M, Waldschmitt N, Poulin LF, Iovanna J, Ryffel B, Rosenstiel P, Chamaillard M. Radulovic K, et al. Among authors: poulin lf. Mucosal Immunol. 2018 May;11(3):811-819. doi: 10.1038/mi.2017.87. Epub 2017 Nov 15. Mucosal Immunol. 2018. PMID: 29139477 Free article.
23 results