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A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa.
Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Jackow J, Rami A, Hansen C, Guo Z, Gaddam S, Pappalardo A, Li L, Cramer A, Roy KR, Nguyen TM, Tanabe K, McGrath PS, Bruckner A, Bilousova G, Roop D, Bailey I, Tang JY, Christiano A, Steinmetz LM, Wernig M, Oro AE. Neumayer G, et al. bioRxiv [Preprint]. 2023 Mar 1:2023.02.28.529447. doi: 10.1101/2023.02.28.529447. bioRxiv. 2023. PMID: 36909618 Free PMC article. Preprint.
Vitiligo non-responding lesions to narrow band UVB have intriguing cellular and molecular abnormalities that may prevent epidermal repigmentation.
Goldstein NB, Steel A, Tomb L, Berk Z, Hu J, Balaya V, Hoaglin L, Ganuthula K, Patel M, Mbika E, Robinson WA, Roop DR, Norris DA, Birlea SA. Goldstein NB, et al. Among authors: roop dr. Pigment Cell Melanoma Res. 2024 May;37(3):378-390. doi: 10.1111/pcmr.13160. Epub 2024 Feb 11. Pigment Cell Melanoma Res. 2024. PMID: 38343115
Loricrin at the Boundary between Inside and Outside.
Ishitsuka Y, Roop DR. Ishitsuka Y, et al. Among authors: roop dr. Biomolecules. 2022 May 6;12(5):673. doi: 10.3390/biom12050673. Biomolecules. 2022. PMID: 35625601 Free PMC article. Review.
The Epidermis: Redox Governor of Health and Diseases.
Ishitsuka Y, Roop DR. Ishitsuka Y, et al. Among authors: roop dr. Antioxidants (Basel). 2021 Dec 26;11(1):47. doi: 10.3390/antiox11010047. Antioxidants (Basel). 2021. PMID: 35052551 Free PMC article. Review.
Loricrin and NRF2 Coordinate Cornification.
Ishitsuka Y, Ogawa T, Nakamura Y, Kubota N, Fujisawa Y, Watanabe R, Okiyama N, Fujimoto M, Roop DR, Ishida-Yamamoto A. Ishitsuka Y, et al. Among authors: roop dr. JID Innov. 2021 Oct 15;2(1):100065. doi: 10.1016/j.xjidi.2021.100065. eCollection 2022 Jan. JID Innov. 2021. PMID: 35024686 Free PMC article.
Loricrin Protects against Chemical Carcinogenesis.
Ogawa T, Ishitsuka Y, Nakamura Y, Watanabe R, Okiyama N, Fujisawa Y, Fujimoto M, Roop DR, Nomura T. Ogawa T, et al. Among authors: roop dr. J Invest Dermatol. 2022 Jul;142(7):2023-2026.e1. doi: 10.1016/j.jid.2021.12.015. Epub 2021 Dec 27. J Invest Dermatol. 2022. PMID: 34968502 Free article. No abstract available.
Ancestral patterns of recessive dystrophic epidermolysis bullosa mutations in Hispanic populations suggest sephardic ancestry.
Warshauer EM, Brown A, Fuentes I, Shortt J, Gignoux C, Montinaro F, Metspalu M, Youssefian L, Vahidnezhad H, Jacków J, Christiano AM, Uitto J, Fajardo-Ramírez ÓR, Salas-Alanis JC, McGrath JA, Consuegra L, Rivera C, Maier PA, Runfeldt G, Behar DM, Skorecki K, Sprecher E, Palisson F, Norris DA, Bruckner AL, Kogut I, Bilousova G, Roop DR. Warshauer EM, et al. Among authors: roop dr. Am J Med Genet A. 2021 Nov;185(11):3390-3400. doi: 10.1002/ajmg.a.62456. Epub 2021 Aug 26. Am J Med Genet A. 2021. PMID: 34435747 Free PMC article.
"Structural imprinting" of the cutaneous immune effector function.
Ishitsuka Y, Roop DR, Ogawa T. Ishitsuka Y, et al. Among authors: roop dr. Tissue Barriers. 2021 Jan 2;9(1):1851561. doi: 10.1080/21688370.2020.1851561. Epub 2020 Dec 3. Tissue Barriers. 2021. PMID: 33270506 Free PMC article. Review.
265 results