Porter NJ - Search Results

1

Iron Heme Enzyme-Catalyzed Cyclopropanations with Diazirines as Carbene Precursors: Computational Explorations of Diazirine Activation and Cyclopropanation Mechanism.

Rogge T, Zhou Q, Porter NJ, Arnold FH, Houk KN. Rogge T, et al. Among authors: porter nj. J Am Chem Soc. 2024 Feb 7;146(5):2959-2966. doi: 10.1021/jacs.3c06030. Epub 2024 Jan 25. J Am Chem Soc. 2024. PMID: 38270588

2

Chemodivergent C(sp³)-H and C(sp²)-H Cyanomethylation Using Engineered Carbene Transferases.

Zhang J, Maggiolo AO, Alfonzo E, Mao R, Porter NJ, Abney N, Arnold FH. Zhang J, et al. Among authors: porter nj. Nat Catal. 2023 Feb;6(2):152-160. doi: 10.1038/s41929-022-00908-x. Epub 2023 Jan 19. Nat Catal. 2023. PMID: 36875868 Free PMC article.

3

The β-subunit of tryptophan synthase is a latent tyrosine synthase.

Almhjell PJ, Johnston KE, Porter NJ, Kennemur JL, Bhethanabotla VC, Ducharme J, Arnold FH. Almhjell PJ, et al. Among authors: porter nj. Nat Chem Biol. 2024 May 14. doi: 10.1038/s41589-024-01619-z. Online ahead of print. Nat Chem Biol. 2024. PMID: 38744987

4

MicroED Structure of a Protoglobin Reactive Carbene Intermediate.

Danelius E, Porter NJ, Unge J, Arnold FH, Gonen T. Danelius E, et al. Among authors: porter nj. J Am Chem Soc. 2023 Apr 5;145(13):7159-7165. doi: 10.1021/jacs.2c12004. Epub 2023 Mar 22. J Am Chem Soc. 2023. PMID: 36948184 Free PMC article.

5

Biocatalytic Carbene Transfer Using Diazirines.

Porter NJ, Danelius E, Gonen T, Arnold FH. Porter NJ, et al. J Am Chem Soc. 2022 May 25;144(20):8892-8896. doi: 10.1021/jacs.2c02723. Epub 2022 May 13. J Am Chem Soc. 2022. PMID: 35561334 Free PMC article.

6

Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics.

Ortega-Liebana MC, Porter NJ, Adam C, Valero T, Hamilton L, Sieger D, Becker CG, Unciti-Broceta A. Ortega-Liebana MC, et al. Among authors: porter nj. Angew Chem Weinheim Bergstr Ger. 2022 Jan 3;134(1):e202111461. doi: 10.1002/ange.202111461. Epub 2021 Nov 18. Angew Chem Weinheim Bergstr Ger. 2022. PMID: 38505566 Free PMC article.

7

Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics.

Ortega-Liebana MC, Porter NJ, Adam C, Valero T, Hamilton L, Sieger D, Becker CG, Unciti-Broceta A. Ortega-Liebana MC, et al. Among authors: porter nj. Angew Chem Int Ed Engl. 2022 Jan 3;61(1):e202111461. doi: 10.1002/anie.202111461. Epub 2021 Nov 18. Angew Chem Int Ed Engl. 2022. PMID: 34730266 Free PMC article.

8

CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury.

Keatinge M, Tsarouchas TM, Munir T, Porter NJ, Larraz J, Gianni D, Tsai HH, Becker CG, Lyons DA, Becker T. Keatinge M, et al. Among authors: porter nj. PLoS Genet. 2021 Apr 29;17(4):e1009515. doi: 10.1371/journal.pgen.1009515. eCollection 2021 Apr. PLoS Genet. 2021. PMID: 33914736 Free PMC article.

9

Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders.

Osko JD, Porter NJ, Decroos C, Lee MS, Watson PR, Raible SE, Krantz ID, Deardorff MA, Christianson DW. Osko JD, et al. Among authors: porter nj. J Struct Biol. 2021 Mar;213(1):107681. doi: 10.1016/j.jsb.2020.107681. Epub 2020 Dec 11. J Struct Biol. 2021. PMID: 33316326 Free PMC article.

10

Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.

Morgen M, Steimbach RR, Géraldy M, Hellweg L, Sehr P, Ridinger J, Witt O, Oehme I, Herbst-Gervasoni CJ, Osko JD, Porter NJ, Christianson DW, Gunkel N, Miller AK. Morgen M, et al. Among authors: porter nj. ChemMedChem. 2020 Jul 3;15(13):1163-1174. doi: 10.1002/cmdc.202000149. Epub 2020 May 13. ChemMedChem. 2020. PMID: 32348628 Free PMC article.

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