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Page 1
Behavioral, metabolic, and lipidomic characterization of the 5xFADxTg30 mouse model of Alzheimer's disease.
Marshall JPS, Huynh K, Lancaster GI, Ng J, Collins JM, Pernes G, Liang A, Featherby T, Mellet NA, Drew BG, Calkin AC, King AE, Meikle PJ, Febbraio MA, Adlard PA, Henstridge DC. Marshall JPS, et al. Among authors: meikle pj. iScience. 2024 Jan 4;27(2):108800. doi: 10.1016/j.isci.2024.108800. eCollection 2024 Feb 16. iScience. 2024. PMID: 38292430 Free PMC article.
Circulating lipid profiles are associated with cross-sectional and longitudinal changes of central biomarkers for Alzheimer's disease.
Kim JP, Nho K, Wang T, Huynh K, Arnold M, Risacher SL, Bice PJ, Han X, Kristal BS, Blach C, Baillie R, Kastenmüller G, Meikle PJ, Saykin AJ, Kaddurah-Daouk R; Alzheimer’s Disease Neuroimaging Initiative; Alzheimer’s Disease Metabolomics Consortium. Kim JP, et al. Among authors: meikle pj. medRxiv [Preprint]. 2023 Jun 21:2023.06.12.23291054. doi: 10.1101/2023.06.12.23291054. medRxiv. 2023. PMID: 37398438 Free PMC article. Preprint.
A Modified Mediterranean Ketogenic Diet mitigates modifiable risk factors of Alzheimer's Disease: a serum and CSF-based metabolic analysis.
Schweickart A, Batra R, Neth BJ, Martino C, Shenhav L, Zhang AR, Shi P, Karu N, Huynh K, Meikle PJ, Schimmel L, Dilmore AH, Blennow K, Zetterberg H, Blach C, Dorrestein PC, Knight R; Alzheimer’s Gut Microbiome Project Consortium; Craft S, Kaddurah-Daouk R, Krumsiek J. Schweickart A, et al. Among authors: meikle pj. medRxiv [Preprint]. 2023 Nov 27:2023.11.27.23298990. doi: 10.1101/2023.11.27.23298990. medRxiv. 2023. PMID: 38076824 Free PMC article. Preprint.
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Among authors: meikle pj. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36.
Barrachina MN, Pernes G, Becker IC, Allaeys I, Hirsch TI, Groeneveld DJ, Khan AO, Freire D, Guo K, Carminita E, Morgan PK, Collins TJ, Mellett NA, Wei Z, Almazni I, Italiano JE, Luyendyk J, Meikle PJ, Puder M, Morgan NV, Boilard E, Murphy AJ, Machlus KR. Barrachina MN, et al. Among authors: meikle pj. bioRxiv [Preprint]. 2023 Feb 12:2023.02.12.527706. doi: 10.1101/2023.02.12.527706. bioRxiv. 2023. PMID: 36798332 Free PMC article. Updated. Preprint.
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data.
Jo T, Kim J, Bice P, Huynh K, Wang T, Arnold M, Meikle PJ, Giles C, Kaddurah-Daouk R, Saykin AJ, Nho K; Alzheimer's Disease Metabolomics Consortium (ADMC); Alzheimer's Disease Neuroimaging Initiative (ADNI). Jo T, et al. Among authors: meikle pj. EBioMedicine. 2023 Nov;97:104820. doi: 10.1016/j.ebiom.2023.104820. Epub 2023 Oct 7. EBioMedicine. 2023. PMID: 37806288 Free PMC article.
A blood-based signature of cerebrospinal fluid Aβ1-42 status.
Goudey B, Fung BJ, Schieber C, Faux NG; Alzheimer’s Disease Metabolomics Consortium; Alzheimer’s Disease Neuroimaging Initiative. Goudey B, et al. Sci Rep. 2019 Mar 11;9(1):4163. doi: 10.1038/s41598-018-37149-7. Sci Rep. 2019. PMID: 30853713 Free PMC article.
Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease.
Baloni P, Funk CC, Yan J, Yurkovich JT, Kueider-Paisley A, Nho K, Heinken A, Jia W, Mahmoudiandehkordi S, Louie G, Saykin AJ, Arnold M, Kastenmüller G, Griffiths WJ, Thiele I; Alzheimer’s Disease Metabolomics Consortium; Kaddurah-Daouk R, Price ND. Baloni P, et al. Cell Rep Med. 2020 Nov 17;1(8):100138. doi: 10.1016/j.xcrm.2020.100138. eCollection 2020 Nov 17. Cell Rep Med. 2020. PMID: 33294859 Free PMC article.
Health economic analysis of polygenic risk score use in primary prevention of coronary artery disease - A system dynamics model.
Vernon ST, Brentnall S, Currie DJ, Peng C, Gray MP, Botta G, Mujwara D, Nicholls SJ, Grieve SM, Redfern J, Chow C, Levesque JF, Meikle PJ, Jennings G, Ademi Z, Wilson A, Figtree GA. Vernon ST, et al. Among authors: meikle pj. Am J Prev Cardiol. 2024 May 18;18:100672. doi: 10.1016/j.ajpc.2024.100672. eCollection 2024 Jun. Am J Prev Cardiol. 2024. PMID: 38828126 Free PMC article.
Ehf controls mammary alveolar lineage differentiation and is a putative suppressor of breast tumorigenesis.
Nightingale R, Reehorst CM, Vukelic N, Papadopoulos N, Liao Y, Guleria S, Bell C, Vaillant F, Paul S, Luk IY, Dhillon AS, Jenkins LJ, Morrow RJ, Jackling FC, Chand AL, Chisanga D, Chen Y, Williams DS, Anderson RL, Ellis S, Meikle PJ, Shi W, Visvader JE, Pal B, Mariadason JM. Nightingale R, et al. Among authors: meikle pj. Dev Cell. 2024 May 20:S1534-5807(24)00298-3. doi: 10.1016/j.devcel.2024.04.022. Online ahead of print. Dev Cell. 2024. PMID: 38781975 Free article.
309 results