Xiao G - Search Results

1

A CANCER PERSISTENT DNA REPAIR CIRCUIT DRIVEN BY MDM2, MDM4 (MDMX), AND MUTANT P53 FOR RECRUITMENT OF MDC1 AND 53BP1 TO CHROMATIN.

Ellison V, Polotskaia A, Xiao G, Leybengrub P, Qiu W, Lee R, Hendrickson R, Hu W, Bargonetti J. Ellison V, et al. Among authors: xiao g. bioRxiv [Preprint]. 2024 Jan 23:2024.01.20.576487. doi: 10.1101/2024.01.20.576487. bioRxiv. 2024. PMID: 38328189 Free PMC article. Preprint.

2

Identification, validation, and targeting of the mutant p53-PARP-MCM chromatin axis in triple negative breast cancer.

Qiu WG, Polotskaia A, Xiao G, Di L, Zhao Y, Hu W, Philip J, Hendrickson RC, Bargonetti J. Qiu WG, et al. Among authors: xiao g. NPJ Breast Cancer. 2017;3:1. doi: 10.1038/s41523-016-0001-7. Epub 2017 Jan 19. NPJ Breast Cancer. 2017. PMID: 28232952 Free PMC article.

3

Contemplations on MDMX (MDM4) driving triple negative breast cancer circulating tumor cells and metastasis.

Gao C, Xiao G, Bargonetti J. Gao C, et al. Among authors: xiao g. Oncotarget. 2019 Aug 20;10(49):5007-5010. doi: 10.18632/oncotarget.27134. eCollection 2019 Aug 20. Oncotarget. 2019. PMID: 31489110 Free PMC article.

4

Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4.

Polotskaia A, Xiao G, Reynoso K, Martin C, Qiu WG, Hendrickson RC, Bargonetti J. Polotskaia A, et al. Among authors: xiao g. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1220-9. doi: 10.1073/pnas.1416318112. Epub 2015 Mar 2. Proc Natl Acad Sci U S A. 2015. PMID: 25733866 Free PMC article.

5

Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer.

Xiao G, Lundine D, Annor GK, Canar J, Ellison V, Polotskaia A, Donabedian PL, Reiner T, Khramtsova GF, Olopade OI, Mazo A, Bargonetti J. Xiao G, et al. Cancer Res. 2020 Feb 1;80(3):394-405. doi: 10.1158/0008-5472.CAN-19-1036. Epub 2019 Nov 27. Cancer Res. 2020. PMID: 31776133 Free PMC article.

6

MDM2-C Functions as an E3 Ubiquitin Ligase.

Kim JY, Lee R, Xiao G, Forbes D, Bargonetti J. Kim JY, et al. Among authors: xiao g. Cancer Manag Res. 2020 Aug 24;12:7715-7724. doi: 10.2147/CMAR.S260943. eCollection 2020. Cancer Manag Res. 2020. PMID: 32904724 Free PMC article.

7

Oligomerization of Mutant p53 R273H is not Required for Gain-of-Function Chromatin Associated Activities.

Annor GK, Elshabassy N, Lundine D, Conde DG, Xiao G, Ellison V, Bargonetti J. Annor GK, et al. Among authors: xiao g. Front Cell Dev Biol. 2021 Nov 22;9:772315. doi: 10.3389/fcell.2021.772315. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34881245 Free PMC article.

8

Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment.

Madorsky Rowdo FP, Xiao G, Khramtsova GF, Nguyen J, Olopade OI, Martini R, Stonaker B, Boateng R, Oppong JK, Adjei EK, Awuah B, Kyei I, Aitpillah FS, Adinku MO, Ankomah K, Osei-Bonsu EB, Gyan KK, Altorki NK, Cheng E, Ginter PS, Hoda S, Newman L, Elemento O, Davis MB, Martin ML, Bargonetti J. Madorsky Rowdo FP, et al. Among authors: xiao g. bioRxiv [Preprint]. 2023 Jun 22:2023.06.22.544406. doi: 10.1101/2023.06.22.544406. bioRxiv. 2023. PMID: 38076873 Free PMC article. Updated. Preprint.

9

Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells.

Gao C, Xiao G, Piersigilli A, Gou J, Ogunwobi O, Bargonetti J. Gao C, et al. Among authors: xiao g. Breast Cancer Res. 2019 Jan 14;21(1):5. doi: 10.1186/s13058-018-1094-8. Breast Cancer Res. 2019. PMID: 30642351 Free PMC article.

10

Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity.

Ellison V, Annor GK, Freedman C, Xiao G, Lundine D, Freulich E, Prives C, Bargonetti J. Ellison V, et al. Among authors: xiao g. Oncotarget. 2021 Jun 8;12(12):1128-1146. doi: 10.18632/oncotarget.27975. eCollection 2021 Jun 8. Oncotarget. 2021. PMID: 34136083 Free PMC article.

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