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Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase.
Kelly AG, Wang W, Rothenberger E, Yang J, Gilligan MM, Kipper FC, Attaya A, Gartung A, Hwang SH, Gillespie MJ, Bayer RL, Quinlivan KM, Torres KL, Huang S, Mitsiades N, Yang H, Hammock BD, Panigrahy D. Kelly AG, et al. Among authors: yang h, yang j. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2314085121. doi: 10.1073/pnas.2314085121. Epub 2024 Feb 8. Proc Natl Acad Sci U S A. 2024. PMID: 38330013 Free PMC article.
Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation.
Wang W, Yang J, Zhang J, Wang Y, Hwang SH, Qi W, Wan D, Kim D, Sun J, Sanidad KZ, Yang H, Park Y, Liu JY, Zhao X, Zheng X, Liu Z, Hammock BD, Zhang G. Wang W, et al. Among authors: yang h, yang j. Proc Natl Acad Sci U S A. 2018 May 15;115(20):5283-5288. doi: 10.1073/pnas.1721711115. Epub 2018 May 1. Proc Natl Acad Sci U S A. 2018. PMID: 29717038 Free PMC article.
Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor.
Gartung A, Yang J, Sukhatme VP, Bielenberg DR, Fernandes D, Chang J, Schmidt BA, Hwang SH, Zurakowski D, Huang S, Kieran MW, Hammock BD, Panigrahy D. Gartung A, et al. Among authors: yang j. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1698-1703. doi: 10.1073/pnas.1803999116. Epub 2019 Jan 15. Proc Natl Acad Sci U S A. 2019. PMID: 30647111 Free PMC article.
Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation.
Ma M, Ren Q, Yang J, Zhang K, Xiong Z, Ishima T, Pu Y, Hwang SH, Toyoshima M, Iwayama Y, Hisano Y, Yoshikawa T, Hammock BD, Hashimoto K. Ma M, et al. Among authors: yang j. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7083-7088. doi: 10.1073/pnas.1819234116. Epub 2019 Mar 19. Proc Natl Acad Sci U S A. 2019. PMID: 30890645 Free PMC article.
Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase.
Pu Y, Yang J, Chang L, Qu Y, Wang S, Zhang K, Xiong Z, Zhang J, Tan Y, Wang X, Fujita Y, Ishima T, Wang D, Hwang SH, Hammock BD, Hashimoto K. Pu Y, et al. Among authors: yang j. Proc Natl Acad Sci U S A. 2020 May 26;117(21):11753-11759. doi: 10.1073/pnas.1922287117. Epub 2020 May 12. Proc Natl Acad Sci U S A. 2020. PMID: 32398374 Free PMC article.
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression.
Fishbein A, Wang W, Yang H, Yang J, Hallisey VM, Deng J, Verheul SML, Hwang SH, Gartung A, Wang Y, Bielenberg DR, Huang S, Kieran MW, Hammock BD, Panigrahy D. Fishbein A, et al. Among authors: yang h, yang j. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21576-21587. doi: 10.1073/pnas.2007412117. Epub 2020 Aug 14. Proc Natl Acad Sci U S A. 2020. PMID: 32801214 Free PMC article.
Eicosanoid regulation of debris-stimulated metastasis.
Deng J, Yang H, Haak VM, Yang J, Kipper FC, Barksdale C, Hwang SH, Gartung A, Bielenberg DR, Subbian S, Ho KK, Ye X, Fan D, Sun Y, Hammock BD, Panigrahy D. Deng J, et al. Among authors: yang h, yang j. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2107771118. doi: 10.1073/pnas.2107771118. Proc Natl Acad Sci U S A. 2021. PMID: 34607951 Free PMC article.
Identification of potent inhibitors of the chicken soluble epoxide hydrolase.
Shihadih DS, Harris TR, Yang J, Merzlikin O, Lee KS, Hammock BD, Morisseau C. Shihadih DS, et al. Among authors: yang j. Bioorg Med Chem Lett. 2015 Jan 15;25(2):276-9. doi: 10.1016/j.bmcl.2014.11.053. Epub 2014 Nov 26. Bioorg Med Chem Lett. 2015. PMID: 25479771 Free PMC article.
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