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Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites.
Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner J, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. Cavallero S, et al. Among authors: mack jj. Sci Adv. 2024 Feb 16;10(7):eadj7481. doi: 10.1126/sciadv.adj7481. Epub 2024 Feb 14. Sci Adv. 2024. PMID: 38354249 Free PMC article.
Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer.
Chattopadhyay A, Yang X, Mukherjee P, Sulaiman D, Fogelman HR, Grijalva V, Dubinett S, Wasler TC, Paul MK, Salehi-Rad R, Mack JJ, Iruela-Arispe ML, Navab M, Fogelman AM, Reddy ST. Chattopadhyay A, et al. Among authors: mack jj. Sci Rep. 2018 Jun 13;8(1):9032. doi: 10.1038/s41598-018-26755-0. Sci Rep. 2018. PMID: 29899427 Free PMC article.
Macrophage COX2 Mediates Efferocytosis, Resolution Reprogramming, and Intestinal Epithelial Repair.
Meriwether D, Jones AE, Ashby JW, Solorzano-Vargas RS, Dorreh N, Noori S, Grijalva V, Ball AB, Semis M, Divakaruni AS, Mack JJ, Herschman HR, Martin MG, Fogelman AM, Reddy ST. Meriwether D, et al. Among authors: mack jj. Cell Mol Gastroenterol Hepatol. 2022;13(4):1095-1120. doi: 10.1016/j.jcmgh.2022.01.002. Epub 2022 Jan 10. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35017061 Free PMC article.
Vascular Injury in the Zebrafish Tail Modulates Blood Flow and Peak Wall Shear Stress to Restore Embryonic Circular Network.
Baek KI, Chang SS, Chang CC, Roustaei M, Ding Y, Wang Y, Chen J, O'Donnell R, Chen H, Ashby JW, Xu X, Mack JJ, Cavallero S, Roper M, Hsiai TK. Baek KI, et al. Among authors: mack jj. Front Cardiovasc Med. 2022 Mar 18;9:841101. doi: 10.3389/fcvm.2022.841101. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35369301 Free PMC article.
Exercise Mitigates Flow Recirculation and Activates Mechanosensitive Transcriptome to Uncover Endothelial SCD1-Catalyzed Anti-Inflammatory Metabolites.
Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner JA, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. Cavallero S, et al. Among authors: mack jj. bioRxiv [Preprint]. 2023 May 3:2023.05.02.539172. doi: 10.1101/2023.05.02.539172. bioRxiv. 2023. PMID: 37205360 Free PMC article. Preprint.
Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis.
Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Briot A, et al. Among authors: mack jj. J Exp Med. 2015 Nov 16;212(12):2147-63. doi: 10.1084/jem.20150603. Epub 2015 Nov 9. J Exp Med. 2015. PMID: 26552708 Free PMC article.
NOTCH1 is a mechanosensor in adult arteries.
Mack JJ, Mosqueiro TS, Archer BJ, Jones WM, Sunshine H, Faas GC, Briot A, Aragón RL, Su T, Romay MC, McDonald AI, Kuo CH, Lizama CO, Lane TF, Zovein AC, Fang Y, Tarling EJ, de Aguiar Vallim TQ, Navab M, Fogelman AM, Bouchard LS, Iruela-Arispe ML. Mack JJ, et al. Nat Commun. 2017 Nov 20;8(1):1620. doi: 10.1038/s41467-017-01741-8. Nat Commun. 2017. PMID: 29158473 Free PMC article.
Endothelial Control of Cerebral Blood Flow.
Ashby JW, Mack JJ. Ashby JW, et al. Among authors: mack jj. Am J Pathol. 2021 Nov;191(11):1906-1916. doi: 10.1016/j.ajpath.2021.02.023. Epub 2021 Mar 10. Am J Pathol. 2021. PMID: 33713686 Free article. Review.
28 results