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Serum biomarker signature is predictive of the risk of hepatocellular cancer in patients with cirrhosis.
El-Serag H, Kanwal F, Ning J, Powell H, Khaderi S, Singal AG, Asrani S, Marrero JA, Amos CI, Thrift AP, Luster M, Alsarraj A, Olivares L, Skapura D, Deng J, Salem E, Najjar O, Yu X, Duong H, Scheurer ME, Ballantyne CM, Kaochar S. El-Serag H, et al. Among authors: skapura d. Gut. 2024 Feb 16:gutjnl-2024-332034. doi: 10.1136/gutjnl-2024-332034. Online ahead of print. Gut. 2024. PMID: 38365278
The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response.
Berchuck JE, Adib E, Abou Alaiwi S, Dash AK, Shin JN, Lowder D, McColl C, Castro P, Carelli R, Benedetti E, Deng J, Robertson M, Baca SC, Bell C, McClure HM, El Zarif T, Davidsohn MP, Lakshminarayanan G, Rizwan K, Skapura DG, Grimm SL, Davis CM, Ehli EA, Kelleher KM, Seo JH, Mitsiades N, Coarfa C, Pomerantz MM, Loda M, Ittmann M, Freedman ML, Kaochar S. Berchuck JE, et al. Among authors: skapura dg. Cancer Res. 2022 Aug 16;82(16):2848-2859. doi: 10.1158/0008-5472.CAN-21-3552. Cancer Res. 2022. PMID: 35731919 Free PMC article.
Inhibition of GATA2 in prostate cancer by a clinically available small molecule.
Kaochar S, Rusin A, Foley C, Rajapakshe K, Robertson M, Skapura D, Mason C, Berman De Ruiz K, Tyryshkin AM, Deng J, Shin JN, Fiskus W, Dong J, Huang S, Navone NM, Davis CM, Ehli EA, Coarfa C, Mitsiades N. Kaochar S, et al. Among authors: skapura d. Endocr Relat Cancer. 2021 Nov 24;29(1):15-31. doi: 10.1530/ERC-21-0085. Endocr Relat Cancer. 2021. PMID: 34636746 Free PMC article.
Novel junctophilin-2 mutation A405S is associated with basal septal hypertrophy and diastolic dysfunction.
Quick AP, Landstrom AP, Wang Q, Beavers DL, Reynolds JO, Barreto-Torres G, Tran V, Showell J, Philippen LE, Morris SA, Skapura D, Bos JM, Pedersen SE, Pautler RG, Ackerman MJ, Wehrens XH. Quick AP, et al. Among authors: skapura d. JACC Basic Transl Sci. 2017 Feb;2(1):56-67. doi: 10.1016/j.jacbts.2016.11.004. JACC Basic Transl Sci. 2017. PMID: 28393127 Free PMC article.
Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814.
Mazzocchi G, Sommese L, Palomeque J, Felice JI, Di Carlo MN, Fainstein D, Gonzalez P, Contreras P, Skapura D, McCauley MD, Lascano EC, Negroni JA, Kranias EG, Wehrens XH, Valverde CA, Mattiazzi A. Mazzocchi G, et al. Among authors: skapura d. J Physiol. 2016 Jun 1;594(11):3005-30. doi: 10.1113/JP271622. Epub 2016 Feb 2. J Physiol. 2016. PMID: 26695843 Free PMC article.
Lack of UCP3 does not affect skeletal muscle mitochondrial function under lipid-challenged conditions, but leads to sudden cardiac death.
Nabben M, van Bree BWJ, Lenaers E, Hoeks J, Hesselink MKC, Schaart G, Gijbels MJJ, Glatz JFC, da Silva GJJ, de Windt LJ, Tian R, Mike E, Skapura DG, Wehrens XHT, Schrauwen P. Nabben M, et al. Among authors: skapura dg. Basic Res Cardiol. 2014;109(6):447. doi: 10.1007/s00395-014-0447-4. Epub 2014 Oct 25. Basic Res Cardiol. 2014. PMID: 25344084 Free PMC article.
29 results