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754 results

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Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis.
Prakasam G, Mishra A, Christie A, Miyata J, Carrillo D, Tcheuyap VT, Ye H, Do QN, Wang Y, Reig Torras O, Butti R, Zhong H, Gagan J, Jones KB, Carroll TJ, Modrusan Z, Durinck S, Requena-Komuro MC, Williams NS, Pedrosa I, Wang T, Rakheja D, Kapur P, Brugarolas J. Prakasam G, et al. Among authors: christie a. J Clin Invest. 2024 Feb 22;134(7):e170559. doi: 10.1172/JCI170559. J Clin Invest. 2024. PMID: 38386415 Free PMC article.
Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis.
Wang SS, Gu YF, Wolff N, Stefanius K, Christie A, Dey A, Hammer RE, Xie XJ, Rakheja D, Pedrosa I, Carroll T, McKay RM, Kapur P, Brugarolas J. Wang SS, et al. Among authors: christie a. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16538-43. doi: 10.1073/pnas.1414789111. Epub 2014 Oct 30. Proc Natl Acad Sci U S A. 2014. PMID: 25359211 Free PMC article.
Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade.
Gu YF, Cohn S, Christie A, McKenzie T, Wolff N, Do QN, Madhuranthakam AJ, Pedrosa I, Wang T, Dey A, Busslinger M, Xie XJ, Hammer RE, McKay RM, Kapur P, Brugarolas J. Gu YF, et al. Among authors: christie a. Cancer Discov. 2017 Aug;7(8):900-917. doi: 10.1158/2159-8290.CD-17-0292. Epub 2017 May 4. Cancer Discov. 2017. PMID: 28473526 Free PMC article.
Determinants of renal cell carcinoma invasion and metastatic competence.
Kim K, Zhou Q, Christie A, Stevens C, Ma Y, Onabolu O, Chintalapati S, Mckenzie T, Tcheuyap VT, Woolford L, Zhang H, Singla N, Parida PK, Marquez-Palencia M, Pedrosa I, Margulis V, Sagalowsky A, Xie Z, Wang T, Durinck S, Modrusan Z, Seshagiri S, Kapur P, Brugarolas J, Malladi S. Kim K, et al. Among authors: christie a. Nat Commun. 2021 Oct 4;12(1):5760. doi: 10.1038/s41467-021-25918-4. Nat Commun. 2021. PMID: 34608135 Free PMC article.
A renal cell carcinoma tumorgraft platform to advance precision medicine.
Elias R, Tcheuyap VT, Kaushik AK, Singla N, Gao M, Reig Torras O, Christie A, Mulgaonkar A, Woolford L, Stevens C, Kettimuthu KP, Pavia-Jimenez A, Boroughs LK, Joyce A, Dakanali M, Notgrass H, Margulis V, Cadeddu JA, Pedrosa I, Williams NS, Sun X, DeBerardinis RJ, Öz OK, Zhong H, Seshagiri S, Modrusan Z, Cantarel BL, Kapur P, Brugarolas J. Elias R, et al. Among authors: christie a. Cell Rep. 2021 Nov 23;37(8):110055. doi: 10.1016/j.celrep.2021.110055. Cell Rep. 2021. PMID: 34818533 Free PMC article.
High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma.
Wolff NC, Pavía-Jiménez A, Tcheuyap VT, Alexander S, Vishwanath M, Christie A, Xie XJ, Williams NS, Kapur P, Posner B, McKay RM, Brugarolas J. Wolff NC, et al. Among authors: christie a. Oncotarget. 2015 Jul 10;6(19):16951-62. doi: 10.18632/oncotarget.4773. Oncotarget. 2015. PMID: 26219258 Free PMC article.
Ontological analyses reveal clinically-significant clear cell renal cell carcinoma subtypes with convergent evolutionary trajectories into an aggressive type.
Cai Q, Christie A, Rajaram S, Zhou Q, Araj E, Chintalapati S, Cadeddu J, Margulis V, Pedrosa I, Rakheja D, McKay RM, Brugarolas J, Kapur P. Cai Q, et al. Among authors: christie a. EBioMedicine. 2020 Jan;51:102526. doi: 10.1016/j.ebiom.2019.10.052. Epub 2019 Dec 16. EBioMedicine. 2020. PMID: 31859241 Free PMC article.
Pancreatic tropism of metastatic renal cell carcinoma.
Singla N, Xie Z, Zhang Z, Gao M, Yousuf Q, Onabolu O, McKenzie T, Tcheuyap VT, Ma Y, Choi J, McKay R, Christie A, Torras OR, Bowman IA, Margulis V, Pedrosa I, Przybycin C, Wang T, Kapur P, Rini B, Brugarolas J. Singla N, et al. Among authors: christie a. JCI Insight. 2020 Apr 9;5(7):e134564. doi: 10.1172/jci.insight.134564. JCI Insight. 2020. PMID: 32271170 Free PMC article.
754 results