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Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis.
Öz HH, Cheng EC, Di Pietro C, Tebaldi T, Biancon G, Zeiss C, Zhang PX, Huang PH, Esquibies SS, Britto CJ, Schupp JC, Murray TS, Halene S, Krause DS, Egan ME, Bruscia EM. Öz HH, et al. Among authors: bruscia em. Cell Rep. 2022 Dec 13;41(11):111797. doi: 10.1016/j.celrep.2022.111797. Cell Rep. 2022. PMID: 36516754 Free PMC article.
Human neutrophil development and functionality are enabled in a humanized mouse model.
Zheng Y, Sefik E, Astle J, Karatepe K, Öz HH, Solis AG, Jackson R, Luo HR, Bruscia EM, Halene S, Shan L, Flavell RA. Zheng Y, et al. Among authors: bruscia em. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2121077119. doi: 10.1073/pnas.2121077119. Epub 2022 Oct 21. Proc Natl Acad Sci U S A. 2022. PMID: 36269862 Free PMC article.
Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells.
Song Y, Shan L, Gbyli R, Liu W, Strowig T, Patel A, Fu X, Wang X, Xu ML, Gao Y, Qin A, Bruscia EM, Tebaldi T, Biancon G, Mamillapalli P, Urbonas D, Eynon E, Gonzalez DG, Chen J, Krause DS, Alderman J, Halene S, Flavell RA. Song Y, et al. Among authors: bruscia em. Science. 2021 Mar 5;371(6533):1019-1025. doi: 10.1126/science.abe2485. Science. 2021. PMID: 33674488 Free PMC article.
Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis.
Schupp JC, Khanal S, Gomez JL, Sauler M, Adams TS, Chupp GL, Yan X, Poli S, Zhao Y, Montgomery RR, Rosas IO, Dela Cruz CS, Bruscia EM, Egan ME, Kaminski N, Britto CJ. Schupp JC, et al. Among authors: bruscia em. Am J Respir Crit Care Med. 2020 Nov 15;202(10):1419-1429. doi: 10.1164/rccm.202004-0991OC. Am J Respir Crit Care Med. 2020. PMID: 32603604 Free PMC article.
32 results