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Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson Syndrome and Toxic epidermal necrolysis.
Gibson A, Ram R, Gangula R, Li Y, Mukherjee E, Palubinsky AM, Campbell CN, Thorne M, Konvinse KC, Choshi P, Deshpande P, Pedretti S, O'Neil RT, Wanjalla CN, Kalams SA, Gaudieri S, Lehloenya RJ, Bailin SS, Chopra A; Jason A Trubiano on behalf of the AUS-SCAR study group; Jonny G Peter on behalf of the AFRI-SCAR and IMARI-Africa study group; Mallal SA, Phillips EJ. Gibson A, et al. Among authors: chopra a. bioRxiv [Preprint]. 2024 Feb 18:2023.11.26.568771. doi: 10.1101/2023.11.26.568771. bioRxiv. 2024. PMID: 38405793 Free PMC article. Preprint.
Cytomegalovirus (CMV) Epitope-Specific CD4+ T Cells Are Inflated in HIV+ CMV+ Subjects.
Abana CO, Pilkinton MA, Gaudieri S, Chopra A, McDonnell WJ, Wanjalla C, Barnett L, Gangula R, Hager C, Jung DK, Engelhardt BG, Jagasia MH, Klenerman P, Phillips EJ, Koelle DM, Kalams SA, Mallal SA. Abana CO, et al. Among authors: chopra a. J Immunol. 2017 Nov 1;199(9):3187-3201. doi: 10.4049/jimmunol.1700851. Epub 2017 Oct 2. J Immunol. 2017. PMID: 28972094 Free PMC article.
HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms.
Konvinse KC, Trubiano JA, Pavlos R, James I, Shaffer CM, Bejan CA, Schutte RJ, Ostrov DA, Pilkinton MA, Rosenbach M, Zwerner JP, Williams KB, Bourke J, Martinez P, Rwandamuriye F, Chopra A, Watson M, Redwood AJ, White KD, Mallal SA, Phillips EJ. Konvinse KC, et al. Among authors: chopra a. J Allergy Clin Immunol. 2019 Jul;144(1):183-192. doi: 10.1016/j.jaci.2019.01.045. Epub 2019 Feb 16. J Allergy Clin Immunol. 2019. PMID: 30776417 Free PMC article.
Single-cell transcriptomics reveal polyclonal memory T-cell responses in skin with positive abacavir patch test results.
Redwood AJ, Rwandamuriye F, Chopra A, Leary S, Ram R, McDonnell W, Konvinse K, White K, Pavlos R, Koelle DM, Mallal S, Phillips EJ. Redwood AJ, et al. Among authors: chopra a. J Allergy Clin Immunol. 2019 Nov;144(5):1413-1416.e7. doi: 10.1016/j.jaci.2019.09.013. Epub 2019 Sep 28. J Allergy Clin Immunol. 2019. PMID: 31574267 Free PMC article. No abstract available.
New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals.
Pavlos R, Deshpande P, Chopra A, Leary S, Strautins K, Nolan D, Thorborn D, Shaefer M, Rauch A, Dunn D, Montaner J, Rachlis A, Almeida CA, Choo L, James I, Redwood AJ, Li Y, Gaudieri S, Mallal SA, Phillips EJ. Pavlos R, et al. Among authors: chopra a. Hum Immunol. 2020 Jun;81(6):300-304. doi: 10.1016/j.humimm.2020.02.011. Epub 2020 Mar 12. Hum Immunol. 2020. PMID: 32173028 Free PMC article.
In chronic infection, HIV gag-specific CD4+ T cell receptor diversity is higher than CD8+ T cell receptor diversity and is associated with less HIV quasispecies diversity.
Pilkinton MA, McDonnell WJ, Barnett L, Chopra A, Gangula R, White KD, Leary S, Currenti J, Gaudieri S, Mallal SA, Kalams SA. Pilkinton MA, et al. Among authors: chopra a. J Virol. 2021 Mar 25;95(8):e02380-20. doi: 10.1128/JVI.02380-20. Epub 2021 Feb 3. J Virol. 2021. PMID: 33536169 Free PMC article.
Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells.
Wanjalla CN, McDonnell WJ, Ram R, Chopra A, Gangula R, Leary S, Mashayekhi M, Simmons JD, Warren CM, Bailin S, Gabriel CL, Guo L, Furch BD, Lima MC, Woodward BO, Hannah L, Pilkinton MA, Fuller DT, Kawai K, Virmani R, Finn AV, Hasty AH, Mallal SA, Kalams SA, Koethe JR. Wanjalla CN, et al. Among authors: chopra a. Cell Rep Med. 2021 Feb 16;2(2):100205. doi: 10.1016/j.xcrm.2021.100205. eCollection 2021 Feb 16. Cell Rep Med. 2021. PMID: 33665640 Free PMC article.
Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: homologous recombination has potential to change SARS-CoV-2 at both protein and RNA level.
Leary S, Gaudieri S, Parker MD, Chopra A, James I, Pakala S, Alves E, John M, Lindsey BB, Keeley AJ, Rowland-Jones SL, Swanson MS, Ostrov DA, Bubenik JL, Das S, Sidney J, Sette A; COVID-19 Genomics UK (COG-UK) consortium; de Silva TI, Phillips E, Mallal S. Leary S, et al. Among authors: chopra a. bioRxiv [Preprint]. 2021 Aug 6:2020.04.10.029454. doi: 10.1101/2020.04.10.029454. bioRxiv. 2021. PMID: 33880475 Free PMC article. Updated. Preprint.
1,650 results