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D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation.
Pianka ST, Li T, Prins TJ, Eldred BSC, Kevan BM, Liang H, Zapanta Rinonos S, Kornblum HI, Nathanson DA, Pellegrini M, Liau LM, Nghiemphu PL, Cloughesy TF, Lai A. Pianka ST, et al. Among authors: pellegrini m. Cancer Res Commun. 2024 Mar 22;4(3):876-894. doi: 10.1158/2767-9764.CRC-23-0271. Cancer Res Commun. 2024. PMID: 38445960 Free PMC article.
The dopamine receptor antagonist trifluoperazine prevents phenotype conversion and improves survival in mouse models of glioblastoma.
Bhat K, Saki M, Vlashi E, Cheng F, Duhachek-Muggy S, Alli C, Yu G, Medina P, He L, Damoiseaux R, Pellegrini M, Zemke NR, Nghiemphu PL, Cloughesy TF, Liau LM, Kornblum HI, Pajonk F. Bhat K, et al. Among authors: pellegrini m. Proc Natl Acad Sci U S A. 2020 May 19;117(20):11085-11096. doi: 10.1073/pnas.1920154117. Epub 2020 May 1. Proc Natl Acad Sci U S A. 2020. PMID: 32358191 Free PMC article.
Gigaxonin Suppresses Epithelial-to-Mesenchymal Transition of Human Cancer Through Downregulation of Snail.
Veena MS, Gahng JJ, Alani M, Ko AY, Basak SK, Liu IY, Hwang KJ, Chatoff JR, Venkatesan N, Morselli M, Yan W, Ali I, Kaczor-Urbanowicz KE, Gowda BS, Frost P, Pellegrini M, Moatamed NA, Wilczynski SP, Bomont P, Wang MB, Shin DS, Srivatsan ES. Veena MS, et al. Among authors: pellegrini m. Cancer Res Commun. 2024 Mar 8;4(3):706-722. doi: 10.1158/2767-9764.CRC-23-0331. Cancer Res Commun. 2024. PMID: 38421310 Free PMC article.
A randomized, phase 1, placebo-controlled trial of APG-157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor-associated microbes.
Basak SK, Bera A, Yoon AJ, Morselli M, Jeong C, Tosevska A, Dong TS, Eklund M, Russ E, Nasser H, Lagishetty V, Guo R, Sajed D, Mudgal S, Mehta P, Avila L, Srivastava M, Faull K, Jacobs J, Pellegrini M, Shin DS, Srivatsan ES, Wang MB. Basak SK, et al. Among authors: pellegrini m. Cancer. 2020 Apr 15;126(8):1668-1682. doi: 10.1002/cncr.32644. Epub 2020 Feb 5. Cancer. 2020. PMID: 32022261 Free article. Clinical Trial.
A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier.
Hilfenhaus G, Mompeón A, Freshman J, Prajapati DP, Hernandez G, Freitas VM, Ma F, Langenbacher AD, Mirkov S, Song D, Cho BK, Goo YA, Pellegrini M, Chen JN, Damoiseaux R, Iruela-Arispe ML. Hilfenhaus G, et al. Among authors: pellegrini m. Cancer Res. 2021 Feb 1;81(3):619-633. doi: 10.1158/0008-5472.CAN-19-3911. Epub 2020 Nov 20. Cancer Res. 2021. PMID: 33218969 Free PMC article.
1,671 results