Baxt LA - Search Results

1

Next Generation Neuropeptide Y Receptor Small Molecule Agonists Inhibit Mosquito Biting Behavior.

Zeledon EV, Baxt LA, Khan TA, Michino M, Miller M, Huggins DJ, Jiang CS, Vosshall LB, Duvall LB. Zeledon EV, et al. Among authors: baxt la. bioRxiv [Preprint]. 2024 Mar 5:2024.02.28.582529. doi: 10.1101/2024.02.28.582529. bioRxiv. 2024. PMID: 38464241 Free PMC article. Preprint.

2

Shape-Based Virtual Screening of a Billion-Compound Library Identifies Mycobacterial Lipoamide Dehydrogenase Inhibitors.

Michino M, Beautrait A, Boyles NA, Nadupalli A, Dementiev A, Sun S, Ginn J, Baxt L, Suto R, Bryk R, Jerome SV, Huggins DJ, Vendome J. Michino M, et al. ACS Bio Med Chem Au. 2023 Sep 8;3(6):507-515. doi: 10.1021/acsbiomedchemau.3c00046. eCollection 2023 Dec 20. ACS Bio Med Chem Au. 2023. PMID: 38144256 Free PMC article.

3

A Chemical Strategy toward Novel Brain-Penetrant EZH2 Inhibitors.

Liang R, Tomita D, Sasaki Y, Ginn J, Michino M, Huggins DJ, Baxt L, Kargman S, Shahid M, Aso K, Duggan M, Stamford AW, DeStanchina E, Liverton N, Meinke PT, Foley MA, Phillips RE. Liang R, et al. ACS Med Chem Lett. 2022 Feb 10;13(3):377-387. doi: 10.1021/acsmedchemlett.1c00448. eCollection 2022 Mar 10. ACS Med Chem Lett. 2022. PMID: 35300079 Free PMC article.

4

Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs.

Kastan NR, Oak S, Liang R, Baxt L, Myers RW, Ginn J, Liverton N, Huggins DJ, Pichardo J, Paul M, Carroll TS, Nagiel A, Gnedeva K, Hudspeth AJ. Kastan NR, et al. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2206113119. doi: 10.1073/pnas.2206113119. Epub 2022 Jul 8. Proc Natl Acad Sci U S A. 2022. PMID: 35867764 Free PMC article.

5

Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1.

Khor B, Conway KL, Omar AS, Biton M, Haber AL, Rogel N, Baxt LA, Begun J, Kuballa P, Gagnon JD, Lassen KG, Regev A, Xavier RJ. Khor B, et al. Among authors: baxt la. J Immunol. 2019 Oct 1;203(7):1820-1829. doi: 10.4049/jimmunol.1800419. Epub 2019 Aug 26. J Immunol. 2019. PMID: 31451676 Free PMC article.

6

RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy.

Heath RJ, Goel G, Baxt LA, Rush JS, Mohanan V, Paulus GLC, Jani V, Lassen KG, Xavier RJ. Heath RJ, et al. Among authors: baxt la. Cell Rep. 2016 Nov 22;17(9):2183-2194. doi: 10.1016/j.celrep.2016.11.005. Cell Rep. 2016. PMID: 27880896 Free PMC article.

7

Intermediate filaments enable pathogen docking to trigger type 3 effector translocation.

Russo BC, Stamm LM, Raaben M, Kim CM, Kahoud E, Robinson LR, Bose S, Queiroz AL, Herrera BB, Baxt LA, Mor-Vaknin N, Fu Y, Molina G, Markovitz DM, Whelan SP, Goldberg MB. Russo BC, et al. Among authors: baxt la. Nat Microbiol. 2016 Mar 7;1:16025. doi: 10.1038/nmicrobiol.2016.25. Nat Microbiol. 2016. PMID: 27572444 Free PMC article.

8

Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk.

Lassen KG, McKenzie CI, Mari M, Murano T, Begun J, Baxt LA, Goel G, Villablanca EJ, Kuo SY, Huang H, Macia L, Bhan AK, Batten M, Daly MJ, Reggiori F, Mackay CR, Xavier RJ. Lassen KG, et al. Among authors: baxt la. Immunity. 2016 Jun 21;44(6):1392-405. doi: 10.1016/j.immuni.2016.05.007. Epub 2016 Jun 7. Immunity. 2016. PMID: 27287411 Free PMC article.

9

Role of Autophagy in the Maintenance of Intestinal Homeostasis.

Baxt LA, Xavier RJ. Baxt LA, et al. Gastroenterology. 2015 Sep;149(3):553-62. doi: 10.1053/j.gastro.2015.06.046. Epub 2015 Jul 11. Gastroenterology. 2015. PMID: 26170139 Free PMC article. Review.

10

Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.

Begun J, Lassen KG, Jijon HB, Baxt LA, Goel G, Heath RJ, Ng A, Tam JM, Kuo SY, Villablanca EJ, Fagbami L, Oosting M, Kumar V, Schenone M, Carr SA, Joosten LA, Vyas JM, Daly MJ, Netea MG, Brown GD, Wijmenga C, Xavier RJ. Begun J, et al. Among authors: baxt la. Cell Rep. 2015 Jun 30;11(12):1905-18. doi: 10.1016/j.celrep.2015.05.045. Epub 2015 Jun 18. Cell Rep. 2015. PMID: 26095365 Free PMC article.

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