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Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis.
Bullard BM, McDonald SJ, Cardaci TD, VanderVeen BN, Mohammed AD, Kubinak JL, Pierre JF, Chatzistamou I, Fan D, Hofseth LJ, Murphy EA. Bullard BM, et al. Among authors: hofseth lj. Am J Physiol Gastrointest Liver Physiol. 2024 May 1;326(5):G591-G606. doi: 10.1152/ajpgi.00004.2024. Epub 2024 Mar 12. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 38469632
The synthetic food dye, Red 40, causes DNA damage, causes colonic inflammation, and impacts the microbiome in mice.
Zhang Q, Chumanevich AA, Nguyen I, Chumanevich AA, Sartawi N, Hogan J, Khazan M, Harris Q, Massey B, Chatzistamou I, Buckhaults PJ, Banister CE, Wirth M, Hebert JR, Murphy EA, Hofseth LJ. Zhang Q, et al. Among authors: hofseth lj. Toxicol Rep. 2023 Sep 6;11:221-232. doi: 10.1016/j.toxrep.2023.08.006. eCollection 2023 Dec. Toxicol Rep. 2023. PMID: 37719200 Free PMC article.
Pharmacokinetics of Panaxynol in Mice.
Tashkandi H, Chaparala A, Peng S, Nagarkatti M, Nagarkatti P, Chumanevich AA, Hofseth LJ. Tashkandi H, et al. Among authors: hofseth lj. J Cancer Sci Clin Ther. 2020;4(2):133-143. doi: 10.26502/jcsct.5079059. Epub 2020 Jun 1. J Cancer Sci Clin Ther. 2020. PMID: 32905447 Free PMC article.
Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice.
Chaparala A, Poudyal D, Tashkandi H, Witalison EE, Chumanevich AA, Hofseth JL, Nguyen I, Hardy O, Pittman DL, Wyatt MD, Windust A, Murphy EA, Nagarkatti M, Nagarkatti P, Hofseth LJ. Chaparala A, et al. Among authors: hofseth lj. Oncotarget. 2020 Jun 2;11(22):2026-2036. doi: 10.18632/oncotarget.27592. eCollection 2020 Jun 2. Oncotarget. 2020. PMID: 32547701 Free PMC article.
Early-onset colorectal cancer: initial clues and current views.
Hofseth LJ, Hebert JR, Chanda A, Chen H, Love BL, Pena MM, Murphy EA, Sajish M, Sheth A, Buckhaults PJ, Berger FG. Hofseth LJ, et al. Nat Rev Gastroenterol Hepatol. 2020 Jun;17(6):352-364. doi: 10.1038/s41575-019-0253-4. Epub 2020 Feb 21. Nat Rev Gastroenterol Hepatol. 2020. PMID: 32086499 Free PMC article. Review.
Acute and short-term administrations of delta-9-tetrahydrocannabinol modulate major gut metabolomic regulatory pathways in C57BL/6 mice.
Oza M, Becker W, Gummadidala PM, Dias T, Omebeyinje MH, Chen L, Mitra C, Jesmin R, Chakraborty P, Sajish M, Hofseth LJ, Banerjee K, Wang Q, Moeller PDR, Nagarkatti M, Nagarkatti P, Chanda A. Oza M, et al. Among authors: hofseth lj. Sci Rep. 2019 Jul 19;9(1):10520. doi: 10.1038/s41598-019-46478-0. Sci Rep. 2019. PMID: 31324830 Free PMC article.
89 results