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Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases.
Henderson SH, Sorrell FJ, Bennett JM, Fedorov O, Hanley MT, Godoi PH, Ruela de Sousa R, Robinson S, Navratilova IH, Elkins JM, Ward SE. Henderson SH, et al. Among authors: elkins jm. Eur J Med Chem. 2024 Apr 5;269:116292. doi: 10.1016/j.ejmech.2024.116292. Epub 2024 Mar 7. Eur J Med Chem. 2024. PMID: 38479168 Free article.
Structure of dystrophia myotonica protein kinase.
Elkins JM, Amos A, Niesen FH, Pike AC, Fedorov O, Knapp S. Elkins JM, et al. Protein Sci. 2009 Apr;18(4):782-91. doi: 10.1002/pro.82. Protein Sci. 2009. PMID: 19309729 Free PMC article.
Type II Inhibitors Targeting CDK2.
Alexander LT, Möbitz H, Drueckes P, Savitsky P, Fedorov O, Elkins JM, Deane CM, Cowan-Jacob SW, Knapp S. Alexander LT, et al. Among authors: elkins jm. ACS Chem Biol. 2015 Sep 18;10(9):2116-25. doi: 10.1021/acschembio.5b00398. Epub 2015 Jul 20. ACS Chem Biol. 2015. PMID: 26158339
Oxalyl Boronates Enable Modular Synthesis of Bioactive Imidazoles.
Lee CF, Holownia A, Bennett JM, Elkins JM, St Denis JD, Adachi S, Yudin AK. Lee CF, et al. Among authors: elkins jm. Angew Chem Int Ed Engl. 2017 May 22;56(22):6264-6267. doi: 10.1002/anie.201611006. Epub 2017 Mar 7. Angew Chem Int Ed Engl. 2017. PMID: 28267269
Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.
Sansook S, Ocasio CA, Day IJ, Tizzard GJ, Coles SJ, Fedorov O, Bennett JM, Elkins JM, Spencer J. Sansook S, et al. Among authors: elkins jm. Org Biomol Chem. 2017 Oct 18;15(40):8655-8660. doi: 10.1039/c7ob02289a. Org Biomol Chem. 2017. PMID: 28984325 Free PMC article.
132 results