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Comparison of a novel potentiator of CFTR channel activity to ivacaftor in ameliorating mucostasis caused by cigarette smoke in primary human bronchial airway epithelial cells.
Tanjala AC, Jiang JX, Eckford PDW, Ramjeesingh M, Li C, Huan LJ, Langeveld G, Townsend C, Paone DV, Busch-Petersen J, Pekhletski R, Tang L, Raju V, Rowe SM, Bear CE. Tanjala AC, et al. Among authors: busch petersen j. bioRxiv [Preprint]. 2024 Mar 4:2024.03.01.582742. doi: 10.1101/2024.03.01.582742. bioRxiv. 2024. PMID: 38496440 Free PMC article. Preprint.
3,5-Disubstituted-indole-7-carboxamides as IKKβ Inhibitors: Optimization of Oral Activity via the C3 Substituent.
Kerns JK, Busch-Petersen J, Fu W, Boehm JC, Nie H, Muratore M, Bullion A, Lin G, Li H, Davis R, Lin X, Lakdawala AS, Cousins R, Field R, Payne J, Miller DD, Bamborough P, Christopher JA, Baldwin I, Osborn RR, Yonchuk J, Webb E, Rumsey WL. Kerns JK, et al. Among authors: busch petersen j. ACS Med Chem Lett. 2018 Oct 30;9(12):1164-1169. doi: 10.1021/acsmedchemlett.8b00291. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613320 Free PMC article.
Tyrosine urea muscarinic acetylcholine receptor antagonists: achiral quaternary ammonium groups.
Jin Q, Davis RS, Bullion AM, Jin J, Wang Y, Widdowson KL, Palovich MR, Foley JJ, Schmidt DB, Buckley PT, Webb EF, Salmon M, Belmonte KE, Sarau HM, Busch-Petersen J. Jin Q, et al. Among authors: busch petersen j. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7087-91. doi: 10.1016/j.bmcl.2012.09.085. Epub 2012 Oct 2. Bioorg Med Chem Lett. 2012. PMID: 23099092
Design, synthesis and structure-activity relationship of N-substituted tropane muscarinic acetylcholine receptor antagonists.
Lainé DI, Yan H, Xie H, Davis RS, Dufour J, Widdowson KL, Palovich MR, Wan Z, Foley JJ, Schmidt DB, Hunsberger GE, Burman M, Bacon AM, Webb EF, Luttmann MA, Salmon M, Sarau HM, Umbrecht ST, Landis PS, Peck BJ, Busch-Petersen J. Lainé DI, et al. Among authors: busch petersen j. Bioorg Med Chem Lett. 2012 May 1;22(9):3366-9. doi: 10.1016/j.bmcl.2012.02.015. Epub 2012 Feb 15. Bioorg Med Chem Lett. 2012. PMID: 22460029
Inhibitors of cathepsin C (dipeptidyl peptidase I).
Laine DI, Busch-Petersen J. Laine DI, et al. Among authors: busch petersen j. Expert Opin Ther Pat. 2010 Apr;20(4):497-506. doi: 10.1517/13543771003657172. Expert Opin Ther Pat. 2010. PMID: 20205619 Review.
Design, synthesis, and structure-activity relationship of tropane muscarinic acetylcholine receptor antagonists.
Lainé DI, Wan Z, Yan H, Zhu C, Xie H, Fu W, Busch-Petersen J, Neipp C, Davis R, Widdowson KL, Blaney FE, Foley J, Bacon AM, Webb EF, Luttmann MA, Burman M, Sarau HM, Salmon M, Palovich MR, Belmonte K. Lainé DI, et al. Among authors: busch petersen j. J Med Chem. 2009 Aug 27;52(16):5241-52. doi: 10.1021/jm900736e. J Med Chem. 2009. PMID: 19630384
Camphor sulfonamide derivatives as novel, potent and selective CXCR3 antagonists.
Wang Y, Busch-Petersen J, Wang F, Kiesow TJ, Graybill TL, Jin J, Yang Z, Foley JJ, Hunsberger GE, Schmidt DB, Sarau HM, Capper-Spudich EA, Wu Z, Fisher LS, McQueney MS, Rivero RA, Widdowson KL. Wang Y, et al. Among authors: busch petersen j. Bioorg Med Chem Lett. 2009 Jan 1;19(1):114-8. doi: 10.1016/j.bmcl.2008.11.008. Epub 2008 Nov 6. Bioorg Med Chem Lett. 2009. PMID: 19014886
Muscarinic acetylcholine receptor antagonists: SAR and optimization of tyrosine ureas.
Jin J, Wang Y, Shi D, Wang F, Fu W, Davis RS, Jin Q, Foley JJ, Sarau HM, Morrow DM, Moore ML, Rivero RA, Palovich M, Salmon M, Belmonte KE, Busch-Petersen J. Jin J, et al. Among authors: busch petersen j. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5481-6. doi: 10.1016/j.bmcl.2008.09.020. Epub 2008 Sep 10. Bioorg Med Chem Lett. 2008. PMID: 18818072
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