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Comparison of a novel potentiator of CFTR channel activity to ivacaftor in ameliorating mucostasis caused by cigarette smoke in primary human bronchial airway epithelial cells.
Tanjala AC, Jiang JX, Eckford PDW, Ramjeesingh M, Li C, Huan LJ, Langeveld G, Townsend C, Paone DV, Busch-Petersen J, Pekhletski R, Tang L, Raju V, Rowe SM, Bear CE. Tanjala AC, et al. Among authors: tang l. bioRxiv [Preprint]. 2024 Mar 4:2024.03.01.582742. doi: 10.1101/2024.03.01.582742. bioRxiv. 2024. PMID: 38496440 Free PMC article. Preprint.
The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibition by Cigarette Smoke.
Raju SV, Lin VY, Liu L, McNicholas CM, Karki S, Sloane PA, Tang L, Jackson PL, Wang W, Wilson L, Macon KJ, Mazur M, Kappes JC, DeLucas LJ, Barnes S, Kirk K, Tearney GJ, Rowe SM. Raju SV, et al. Among authors: tang l. Am J Respir Cell Mol Biol. 2017 Jan;56(1):99-108. doi: 10.1165/rcmb.2016-0226OC. Am J Respir Cell Mol Biol. 2017. PMID: 27585394 Free PMC article.
Evaluation of a novel CFTR potentiator in COPD ferrets with acquired CFTR dysfunction.
Kaza N, Lin VY, Stanford D, Hussain SS, Falk Libby E, Kim H, Borgonovi M, Conrath K, Mutyam V, Byzek SA, Tang LP, Trombley JE, Rasmussen L, Schoeb T, Leung HM, Tearney GJ, Raju SV, Rowe SM. Kaza N, et al. Among authors: tang lp. Eur Respir J. 2022 Jul 13;60(1):2101581. doi: 10.1183/13993003.01581-2021. Print 2022 Jul. Eur Respir J. 2022. PMID: 34916262 Free PMC article.
Ivacaftor Reverses Airway Mucus Abnormalities in a Rat Model Harboring a Humanized G551D-CFTR.
Birket SE, Davis JM, Fernandez-Petty CM, Henderson AG, Oden AM, Tang L, Wen H, Hong J, Fu L, Chambers A, Fields A, Zhao G, Tearney GJ, Sorscher EJ, Rowe SM. Birket SE, et al. Among authors: tang l. Am J Respir Crit Care Med. 2020 Nov 1;202(9):1271-1282. doi: 10.1164/rccm.202002-0369OC. Am J Respir Crit Care Med. 2020. PMID: 32584141 Free PMC article.
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