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DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma.
Kirk AM, Crawford JC, Chou CH, Guy C, Pandey K, Kozlik T, Shah RK, Chung S, Nguyen P, Zhang X, Wang J, Bell M, Mettelman RC, Allen EK, Pogorelyy MV, Kim H, Minervina AA, Awad W, Bajracharya R, White T, Long D Jr, Gordon B, Morrison M, Glazer ES, Murphy AJ, Jiang Y, Fitzpatrick EA, Yarchoan M, Sethupathy P, Croft NP, Purcell AW, Federico SM, Stewart E, Gottschalk S, Zamora AE, DeRenzo C, Strome SE, Thomas PG. Kirk AM, et al. Among authors: thomas pg. Cell Rep Med. 2024 Mar 19;5(3):101469. doi: 10.1016/j.xcrm.2024.101469. Cell Rep Med. 2024. PMID: 38508137 Free PMC article.
Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.
Valkenburg SA, Gras S, Guillonneau C, La Gruta NL, Thomas PG, Purcell AW, Rossjohn J, Doherty PC, Turner SJ, Kedzierska K. Valkenburg SA, et al. Among authors: thomas pg. PLoS Pathog. 2010 Aug 12;6(8):e1001039. doi: 10.1371/journal.ppat.1001039. PLoS Pathog. 2010. PMID: 20711359 Free PMC article.
Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels.
Sanders CJ, Vogel P, McClaren JL, Bajracharya R, Doherty PC, Thomas PG. Sanders CJ, et al. Among authors: thomas pg. Am J Physiol Lung Cell Mol Physiol. 2013 Apr 1;304(7):L481-8. doi: 10.1152/ajplung.00343.2012. Epub 2013 Jan 25. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 23355384 Free PMC article.
Immunity to influenza. Preventing infection and regulating disease.
Allen EK, Thomas PG. Allen EK, et al. Among authors: thomas pg. Am J Respir Crit Care Med. 2015 Feb 1;191(3):248-51. doi: 10.1164/rccm.201412-2245ED. Am J Respir Crit Care Med. 2015. PMID: 25635487 Free PMC article. No abstract available.
Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.
Kohlhapp FJ, Huelsmann EJ, Lacek AT, Schenkel JM, Lusciks J, Broucek JR, Goldufsky JW, Hughes T, Zayas JP, Dolubizno H, Sowell RT, Kühner R, Burd S, Kubasiak JC, Nabatiyan A, Marshall S, Bommareddy PK, Li S, Newman JH, Monken CE, Shafikhani SH, Marzo AL, Guevara-Patino JA, Lasfar A, Thomas PG, Lattime EC, Kaufman HL, Zloza A. Kohlhapp FJ, et al. Among authors: thomas pg. Cell Rep. 2016 Oct 18;17(4):957-965. doi: 10.1016/j.celrep.2016.09.068. Cell Rep. 2016. PMID: 27760326 Free PMC article.
Cell-Intrinsic Barriers of T Cell-Based Immunotherapy.
Ghoneim HE, Zamora AE, Thomas PG, Youngblood BA. Ghoneim HE, et al. Among authors: thomas pg. Trends Mol Med. 2016 Dec;22(12):1000-1011. doi: 10.1016/j.molmed.2016.10.002. Epub 2016 Nov 4. Trends Mol Med. 2016. PMID: 27825667 Free PMC article. Review.
Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention.
Smallwood HS, Duan S, Morfouace M, Rezinciuc S, Shulkin BL, Shelat A, Zink EE, Milasta S, Bajracharya R, Oluwaseum AJ, Roussel MF, Green DR, Pasa-Tolic L, Thomas PG. Smallwood HS, et al. Among authors: thomas pg. Cell Rep. 2017 May 23;19(8):1640-1653. doi: 10.1016/j.celrep.2017.04.039. Cell Rep. 2017. PMID: 28538182 Free PMC article.
363 results