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A Phase 2 Clinical Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of Different Prime-Boost Vaccination Schedules of 2013 and 2017 A(H7N9) Inactivated Influenza Virus Vaccines Administered with and without AS03 Adjuvant in Healthy US Adults.
Clin Infect Dis. 2024 Mar 27:ciae173. doi: 10.1093/cid/ciae173. Online ahead of print.
Clin Infect Dis. 2024.
PMID: 38537255
Immunogenicity and safety of varying dosages of a fifth-wave influenza A/H7N9 inactivated vaccine given with and without AS03 adjuvant in healthy adults.
Jackson LA, Stapleton JT, Walter EB, Chen WH, Rouphael NG, Anderson EJ, Neuzil KM, Winokur PL, Smith MJ, Schmader KE, Swamy GK, Thompson AB, Mulligan MJ, Rostad CA, Cross K, Tsong R, Wegel A, Roberts PC.
Jackson LA, et al. Among authors: wegel a.
Vaccine. 2024 Jan 12;42(2):295-309. doi: 10.1016/j.vaccine.2023.12.001. Epub 2023 Dec 16.
Vaccine. 2024.
PMID: 38105137
Free article.
Clinical Trial.
Item in Clipboard
Safety and Immunogenicity of a Delayed Heterologous Avian Influenza A(H7N9) Vaccine Boost Following Different Priming Regimens: A Randomized Clinical Trial.
El Sahly HM, Yildirim I, Frey SE, Winokur P, Jackson LA, Bernstein DI, Creech CB, Chen WH, Rupp RE, Whitaker JA, Phadke V, Hoft DF, Ince D, Brady RC, Edwards KM, Ortiz JR, Berman MA, Weiss J, Wegel A; DMID 17-0090 Study Group.
El Sahly HM, et al. Among authors: wegel a.
J Infect Dis. 2024 Feb 14;229(2):327-340. doi: 10.1093/infdis/jiad276.
J Infect Dis. 2024.
PMID: 37466221
Clinical Trial.
Item in Clipboard
A Multicenter, Controlled Human Infection Study of Influenza A(H1N1)pdm09 in Healthy Adults.
Ortiz JR, Bernstein DI, Hoft DF, Woods CW, McClain MT, Frey SE, Brady RC, Bryant C, Wegel A, Frenck RW, Walter EB, Abate G, Williams SR, Atmar RL, Keitel WA, Rouphael N, Memoli MJ, Makhene MK, Roberts PC, Neuzil KM.
Ortiz JR, et al. Among authors: wegel a.
J Infect Dis. 2023 Aug 11;228(3):287-298. doi: 10.1093/infdis/jiad021.
J Infect Dis. 2023.
PMID: 36702771
Free PMC article.
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Safety and Immunogenicity of Influenza A/H5N8 Virus Vaccine in Healthy Adults: Durability and Cross-reactivity of Antibody Responses.
Neuzil KM, Anderson EJ, Frenck RW, Frey SE, Walter EB, Rupp R, Rotrosen ET, Rouphael NG, Brady RC, Graham I, Schmader KE, Porterfield L, Ortiz JR, Swamy GK, El Sahly HM, Jeevan T, Sitaula R, Wegel A, Webby RJ, Bryant C; Influenza A/H5N8 Virus Vaccine Group.
Neuzil KM, et al. Among authors: wegel a.
Clin Infect Dis. 2023 Jan 5:ciac982. doi: 10.1093/cid/ciac982. Online ahead of print.
Clin Infect Dis. 2023.
PMID: 36610728
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Safety and immunogenicity of monovalent H7N9 influenza vaccine with AS03 adjuvant given sequentially or simultaneously with a seasonal influenza vaccine: A randomized clinical trial.
Ortiz JR, Spearman PW, Goepfert PA, Cross K, Buddy Creech C, Chen WH, Parker S, Overton ET, Dickey M, Logan HL, Wegel A, Neuzil KM.
Ortiz JR, et al. Among authors: wegel a.
Vaccine. 2022 May 20;40(23):3253-3262. doi: 10.1016/j.vaccine.2022.03.055. Epub 2022 Apr 22.
Vaccine. 2022.
PMID: 35465983
Free PMC article.
Clinical Trial.
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Topical Imiquimod Does Not Provide an Adjuvant Effect When Administered With Inactivated Influenza A/H5N1 Vaccine in Healthy Young Adults.
El Sahly HM, Atmar RL, Sendra E, Wegel A, Keitel WA.
El Sahly HM, et al. Among authors: wegel a.
J Infect Dis. 2021 Nov 22;224(10):1712-1719. doi: 10.1093/infdis/jiab206.
J Infect Dis. 2021.
PMID: 33852718
Free PMC article.
Clinical Trial.
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