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Page 1
Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing.
Maneix L, Iakova P, Lee CG, Moree SE, Lu X, Datar GK, Hill CT, Spooner E, King JCK, Sykes DB, Saez B, Di Stefano B, Chen X, Krause DS, Sahin E, Tsai FTF, Goodell MA, Berk BC, Scadden DT, Catic A. Maneix L, et al. Among authors: scadden dt. Nat Cell Biol. 2024 Apr;26(4):593-603. doi: 10.1038/s41556-024-01387-x. Epub 2024 Mar 29. Nat Cell Biol. 2024. PMID: 38553595 Free PMC article.
Bone marrow adipocytes fuel emergency hematopoiesis after myocardial infarction.
Zhang S, Paccalet A, Rohde D, Cremer S, Hulsmans M, Lee IH, Mentkowski K, Grune J, Schloss MJ, Honold L, Iwamoto Y, Zheng Y, Bredella MA, Buckless C, Ghoshhajra B, Thondapu V, van der Laan AM, Piek JJ, Niessen HWM, Pallante F, Carnevale R, Perrotta S, Carnevale D, Iborra-Egea O, Muñoz-Guijosa C, Galvez-Monton C, Bayes-Genis A, Vidoudez C, Trauger SA, Scadden D, Swirski FK, Moskowitz MA, Naxerova K, Nahrendorf M. Zhang S, et al. Nat Cardiovasc Res. 2023 Dec;2(12):1277-1290. doi: 10.1038/s44161-023-00388-7. Epub 2023 Dec 5. Nat Cardiovasc Res. 2023. PMID: 38344689
Biotech leaders call for free press.
Cohen R, Holtzman S, Levin JM, Maraganore JM; Signatories to the Statement. Cohen R, et al. Nat Biotechnol. 2018 Oct 11;36(10):920-922. doi: 10.1038/nbt.4271. Nat Biotechnol. 2018. PMID: 30307914 No abstract available.
Chinese scientists and US leadership in the life sciences.
Holtzman SH, Cohen R, Levin JM, Maraganore J; Signatories to the Statement. Holtzman SH, et al. Nat Biotechnol. 2019 Nov;37(11):1261-1263. doi: 10.1038/s41587-019-0285-x. Nat Biotechnol. 2019. PMID: 31582856 No abstract available.
Cell of origin epigenetic priming determines susceptibility to Tet2 mutation.
Schiroli G, Kartha V, Duarte FM, Kristiansen TA, Mayerhofer C, Shrestha R, Earl A, Hu Y, Tay T, Rhee C, Buenrostro JD, Scadden DT. Schiroli G, et al. Among authors: scadden dt. Nat Commun. 2024 May 21;15(1):4325. doi: 10.1038/s41467-024-48508-6. Nat Commun. 2024. PMID: 38773071 Free PMC article.
A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate.
Bonora M, Morganti C, van Gastel N, Ito K, Calura E, Zanolla I, Ferroni L, Zhang Y, Jung Y, Sales G, Martini P, Nakamura T, Lasorsa FM, Finkel T, Lin CP, Zavan B, Pinton P, Georgakoudi I, Romualdi C, Scadden DT, Ito K. Bonora M, et al. Among authors: scadden dt. Cell Stem Cell. 2024 Mar 7;31(3):359-377.e10. doi: 10.1016/j.stem.2024.02.004. Cell Stem Cell. 2024. PMID: 38458178 Free article.
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia mice.
Saha A, Palchaudhuri R, Lanieri L, Hyzy S, Riddle MJ, Panthera J, Eide CR, Tolar J, Panoskaltsis-Mortari A, Gorfinkel L, Tkachev V, Gerdemann U, Alvarez-Calderon F, Palato ER, MacMillan ML, Wagner JE, Kean LS, Osborn MJ, Kiem HP, Scadden DT, Olson LM, Blazar BR. Saha A, et al. Among authors: scadden dt. Blood. 2024 May 23;143(21):2201-2216. doi: 10.1182/blood.2023023549. Blood. 2024. PMID: 38447038
Stromal Cell Isolation from Hematopoietic Organs.
Kristiansen T, Mayerhofer C, Gustafsson K, Scadden DT. Kristiansen T, et al. Among authors: scadden dt. J Vis Exp. 2024 Jan 26;(203). doi: 10.3791/66231. J Vis Exp. 2024. PMID: 38345255
Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions.
Mei S, Alchahin AM, Tsea I, Kfoury Y, Hirz T, Jeffries NE, Zhao T, Xu Y, Zhang H, Sarkar H, Wu S, Subtelny AO, Johnsen JI, Zhang Y, Salari K, Wu CL, Randolph MA, Scadden DT, Dahl DM, Shin J, Kharchenko PV, Saylor PJ, Sykes DB, Baryawno N. Mei S, et al. Among authors: scadden dt. Genome Med. 2024 Jan 29;16(1):1. doi: 10.1186/s13073-023-01272-6. Genome Med. 2024. PMID: 38281962 Free PMC article.
Health Consequences of Thymus Removal in Adults. Reply.
Kooshesh KA, Gustafsson K, Scadden DT. Kooshesh KA, et al. Among authors: scadden dt. N Engl J Med. 2023 Nov 2;389(18):1726-1727. doi: 10.1056/NEJMc2310640. N Engl J Med. 2023. PMID: 37913517 No abstract available.
381 results