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Design of BET Inhibitor Bottlebrush Prodrugs with Superior Efficacy and Devoid of Systemic Toxicities.
Vohidov F, Andersen JN, Economides KD, Shipitsin MV, Burenkova O, Ackley JC, Vangamudi B, Nguyen HV, Gallagher NM, Shieh P, Golder MR, Liu J, Dahlberg WK, Ehrlich DJC, Kim J, Kristufek SL, Huh SJ, Neenan AM, Baddour J, Paramasivan S, de Stanchina E, Kc G, Turnquist DJ, Saucier-Sawyer JK, Kopesky PW, Brady SW, Jessel MJ, Reiter LA, Chickering DE, Johnson JA, Blume-Jensen P. Vohidov F, et al. Among authors: shieh p. J Am Chem Soc. 2021 Mar 31;143(12):4714-4724. doi: 10.1021/jacs.1c00312. Epub 2021 Mar 19. J Am Chem Soc. 2021. PMID: 33739832 Free PMC article.
Cleavable comonomers enable degradable, recyclable thermoset plastics.
Shieh P, Zhang W, Husted KEL, Kristufek SL, Xiong B, Lundberg DJ, Lem J, Veysset D, Sun Y, Nelson KA, Plata DL, Johnson JA. Shieh P, et al. Nature. 2020 Jul;583(7817):542-547. doi: 10.1038/s41586-020-2495-2. Epub 2020 Jul 22. Nature. 2020. PMID: 32699399 Free PMC article.
241 results